Monoclonal Antibodies 3D structures

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Line 8: Line 8:
*Human Fab
*Human Fab
-
**[[3n9g]], [[3giz]], [[3eo9]], [[1ad9]], [[2fb4]], [[2ig2]], [[1qlr]], [[2zkh]], [[1qbl]], [[1igi]], [[5nst]], [[6amj]], [[6cr1]], [[6h9x]], [[6rco]], [[6rcq]], [[6rcs]], [[6tcm]], [[6tcn]], [[6umh]], [[6umi]], [[6umj]] – hFab mAb - human<br />
+
**[[3n9g]], [[3giz]], [[3eo9]], [[1ad9]], [[2fb4]], [[2ig2]], [[1qlr]], [[2zkh]], [[1qbl]], [[1igi]], [[3kyk]], [[3kym]], [[3nfs]], [[3w9d]], [[5i76]], [[5nst]], [[5od8]], [[5odb]], [[5xrq]], [[6amj]], [[6cr1]], [[6h9x]], [[6rco]], [[6rcq]], [[6rcs]], [[6tcm]], [[6tcn]], [[6umh]], [[6umi]], [[6umj]], [[6wvz]], [[7dun]], [[7km6]], [[7n6p]], [[7pkl]], [[7ven]], [[8jep]], [[8jeq]] – hFab mAb - human<br />
**[[6amm]], [[6anp]], [[6ao0]], [[6tcp]], [[6tcq]] – hFab (mutant)<br />
**[[6amm]], [[6anp]], [[6ao0]], [[6tcp]], [[6tcq]] – hFab (mutant)<br />
-
**[[3qhz]], [[4fql]], [[4gxv]], [[6btj]] - hFab anti-influenza<br />
 
-
**[[3qhf]] – hFab anti-influenza (mutant)<br />
 
**[[3qct]] – hFab anti-lysophosphatidic acid<br />
**[[3qct]] – hFab anti-lysophosphatidic acid<br />
-
**[[3inu]], [[6n7u]] – hFab anti-Ebola<br />
 
**[[5jrp]] – hFab anti-Marburg virus<br />
**[[5jrp]] – hFab anti-Marburg virus<br />
-
**[[3u6r]], [[1nlb]], [[6meg]], [[6med]], [[6mee]], [[6mef]], [[6wo5]], [[6x9x]] - hFab anti-hepatitis C virus<br />
+
**[[3u6r]], [[1nlb]], [[6meg]], [[6med]], [[6mee]], [[6mef]], [[6wo5]], [[6x9x]], [[8tfe]] - hFab anti-hepatitis C virus<br />
 +
**[[5cgy]], [[5chn]] – hFab anti-Chikungunya glycoproteins <br />
 +
**[[4udf]] – hFab anti-parechovirus glycoproteins – Cryo EM<br />
**[[1b4j]] - hFab anti-γ- interferon<br />
**[[1b4j]] - hFab anti-γ- interferon<br />
**[[6w73]] - hFab anti-CD4<br />
**[[6w73]] - hFab anti-CD4<br />
Line 23: Line 22:
**[[1x9q]] - hFab anti-fluorescin<br />
**[[1x9q]] - hFab anti-fluorescin<br />
**[[2d7t]] - hFab anti-hydroxybutyrate<br />
**[[2d7t]] - hFab anti-hydroxybutyrate<br />
-
**[[2fjf]], [[7lsi]] - hFab anti-VEGF<br />
+
**[[2fjf]], [[7lsb]], [[7lsi]] - hFab anti-VEGF<br />
**[[2gjj]] - hFab anti-ERBB-2<br />
**[[2gjj]] - hFab anti-ERBB-2<br />
**[[4g6k]] - hFab anti-interleukin-1<br />
**[[4g6k]] - hFab anti-interleukin-1<br />
Line 29: Line 28:
**[[4lkc]] – hFab anti-PCSK9<br />
**[[4lkc]] – hFab anti-PCSK9<br />
**[[5dk3]] – hFab anti-cell death-1 receptor<br />
**[[5dk3]] – hFab anti-cell death-1 receptor<br />
 +
**[[8tjt]] – hFab anti-glucagon receptor<br />
**[[3ls5]] – hFab anti-tetrahydrocannabinol<br />
**[[3ls5]] – hFab anti-tetrahydrocannabinol<br />
**[[4g5z]] – hFab canakinumab<br />
**[[4g5z]] – hFab canakinumab<br />
**[[1fh5]] – hFab Mak33<br />
**[[1fh5]] – hFab Mak33<br />
-
**[[3hmw]] - hFab ustekinumab <br />
 
**[[3hmw]] - hFab ustekinumab <br />
**[[3hmw]] - hFab ustekinumab <br />
**[[4k7p]] – hFab rhumab6 + mFab 10C4<br />
**[[4k7p]] – hFab rhumab6 + mFab 10C4<br />
**[[6hud]] – hFab anti-amyloidosis – Cryo EM<br />
**[[6hud]] – hFab anti-amyloidosis – Cryo EM<br />
**[[6srv]], [[6srx]], [[6ss0]], [[6tul]] - hFab anti-arginase <br />
**[[6srv]], [[6srx]], [[6ss0]], [[6tul]] - hFab anti-arginase <br />
-
**[[6e65]] – hFab anti-malaria<br />
 
**[[7bm5]] – hFab anti-BamA<br />
**[[7bm5]] – hFab anti-BamA<br />
**[[7km6]] – hFab anti-APOBEC3B<br />
**[[7km6]] – hFab anti-APOBEC3B<br />
-
**[[6u1t]] - mFab anti-Nipa virus<br />
+
**[[2yk1]], [[2ykl]] – hFab anti-nicotine<br />
 +
**[[4nzu]] – hFab anti-myeloma<br />
 +
**[[6mtx]], [[6mty]], [[6nis]] - hFab anti-zika virus<br />
 +
**[[6ws6]] - hFab anti-sarbecovirus<br />
 +
**[[7kba]] - hFab anti-HCMV<br />
 +
**[[5bvj]], [[5bvp]] – hFab anti-IL-1beta<br />
 +
**[[8ry2]] – hFab anti-IL-2<br />
 +
**[[8g2o]] – hFab anti-APOE<br />
 +
**[[8w9h]] – hFab anti-CLEC12A<br />
 +
**[[8dkf]] – hFab anti-glycan<br />
 +
**[[8dkf]] – hFab anti-OX40<br />
 +
**[[7s08]], [[7s0j]], [[8sga]] – hFab anti-Epstein-Barr virus<br />
 +
**[[8tfq]] - hFab anti-fentanyl <br />
 +
**[[8jbj]] - hFab anti-PVRIG <br />
*Mouse Fab
*Mouse Fab
Line 61: Line 72:
**[[1mqk]] - mFab anti-cytochrome C oxidase<br />
**[[1mqk]] - mFab anti-cytochrome C oxidase<br />
**[[1p4i]] – mFab anti-GCN4 peptide<br />
**[[1p4i]] – mFab anti-GCN4 peptide<br />
-
**[[1psk]] – mFab anti-GD2 ganglioside<br />
+
**[[1psk]], [[3vfg]] – mFab anti-GD2 ganglioside<br />
**[[1rih]] – mFab anti-glycolyl GM3<br />
**[[1rih]] – mFab anti-glycolyl GM3<br />
**[[2aab]] – mFab anti-idiotypic<br />
**[[2aab]] – mFab anti-idiotypic<br />
Line 70: Line 81:
**[[4tuo]], [[4trp]] – mFab anti-neuroblastoma<br />
**[[4tuo]], [[4trp]] – mFab anti-neuroblastoma<br />
**[[4qt5]] – mFab anti-TSH receptor<br />
**[[4qt5]] – mFab anti-TSH receptor<br />
-
**[[4oz4]] – mFab anti-tau protein<br />
+
**[[5mx3]] – mFab anti-tau protein<br />
**[[2v7h]] – mFab anti-mannopyranoside<br />
**[[2v7h]] – mFab anti-mannopyranoside<br />
**[[2xkn]] - mFab anti-EGFR<br />
**[[2xkn]] - mFab anti-EGFR<br />
Line 87: Line 98:
**[[3ojd]] – mFab anti-indolicidin<br />
**[[3ojd]] – mFab anti-indolicidin<br />
**[[6bpb]], [[6bpd]] – mFab anti-Vivax invasion<br />
**[[6bpb]], [[6bpd]] – mFab anti-Vivax invasion<br />
-
**[[3gk8]], [[1m71]], [[12e8]], [[1yuh]], [[1fgn]], [[1a6t]], [[4isv]], [[4jj5]], [[3gnm]], [[1ae6]], [[3c5s]], [[1mam]], [[3vg0]], [[4kph]], [[1mlb]], [[2vl5]], [[1rmf]], [[2adg]], [[1s5i]], [[1f8t]], [[4dvb]], [[6dc7]], [[6fab]], [[6lkt]], [[6wt3]], [[6y54]], [[7c95]] – mFab <br />
+
**[[1a6t]], [[1ae6]], [[1f8t]], [[1fgn]], [[1m71]], [[1mam]], [[1mlb]], [[12e8]], [[1rmf]], [[1s5l]], [[1yuh]], [[2adg]], [[2vl5]], [[4isv]], [[4jj5]], [[3gnm]], [[3c5s]], [[3vg0]], [[3gk8]], [[3sgd]], [[4dvb]], [[4kph]], [[4otx]], [[4poz]], [[4s1d]], [[4s2s]], [[5dq9]], [[5h2b]], [[6c5h]], [[6c5i]], [[6c5j]], [[6c5k]], [[6dc7]], [[6fab]], [[6kx0]], [[6p4y]], [[6wt3]], [[6y54]], [[7c95]], [[7jvd]] – mFab <br />
**[[3c08]], [[1yy8]] - mFab commercial<br />
**[[3c08]], [[1yy8]] - mFab commercial<br />
-
**[[6a76]] - mFab anti-ROBO1<br />
+
**[[3wii]], [[6a76]] - mFab anti-ROBO1<br />
**[[6vrt]] - mFab anti-metal<br />
**[[6vrt]] - mFab anti-metal<br />
**[[6fbj]] - mFab anti-matrix melalloproteinase<br />
**[[6fbj]] - mFab anti-matrix melalloproteinase<br />
**[[6gxx]], [[6i1o]], [[6qu9]] - mFab anti-antitrypsin<br />
**[[6gxx]], [[6i1o]], [[6qu9]] - mFab anti-antitrypsin<br />
-
**[[6dg2]] – mFab anti-Ebola<br />
 
**[[6lkt]], [[6ltg]] – mFab anti-herpesvirus<br />
**[[6lkt]], [[6ltg]] – mFab anti-herpesvirus<br />
-
**[[6d9g]] – mFab anti-serotonin transporter<br />
+
**[[5i30]] – mFab anti-astrovirus<br />
 +
**[[5i66]], [[6d9g]] – mFab anti-serotonin transporter<br />
**[[7bg1]] – mFab anti-FLAG<br />
**[[7bg1]] – mFab anti-FLAG<br />
**[[6wx1]] – mFab anti-hemorrhagic fever virus<br />
**[[6wx1]] – mFab anti-hemorrhagic fever virus<br />
 +
**[[3we6]], [[3wfh]], [[3whx]], [[3wif]] – mFab anti-prostaglandin<br />
 +
**[[5cma]] – mFab anti-B7-H3<br />
 +
**[[6u1t]] - mFab anti-Nipa virus<br />
 +
**[[4x80]], [[4x8j]] – mFab anti-ADAMTS5<br />
 +
**[[4wcy]] – mFab AZ130<br />
 +
**[[4ouu]] – mFab anti-MT1-MMP<br />
 +
**[[5az2]] – mFab anti-epiregulin<br />
 +
**[[8doz]] – mFab anti-conococcal lipooligosaccharide<br />
 +
**[[8gkj]], [[8gkk]] – mFab anti-MUC16<br />
 +
**[[8gkl]] – hmFab anti-MUC16<br />
 +
**[[6h3h]] - mFab anti-fullerene<br />
 +
**[[6pyc]] - mFab anti-kappa<br />
 +
**[[6idh]], [[6kdh]] - mFab anti-photoproduct<br />
 +
**[[8s6e]] - mFab anti-Neisseria meningitis<br />
 +
**[[8qxc]] - mFab anti-penicillin<br />
 +
**[[8tca]] - mFab anti-M6A<br />
 +
 +
*Synthetic Fab
 +
 +
**[[7tqa]] – syFab - synthetic<br />
 +
**[[7tqb]] – syFab + DNA + RNA<br />
 +
**[[6df0]], [[6dez]] - syFab anti-phosphotyrosine <br />
 +
**[[6df1]], [[6df2]] - syFab anti-phosphotyrosine + phosphotyrosine peptide<br />
 +
**[[7sqo]] – syscFv in orexin receptor – Cryo EM<br />
 +
*Anti-HIV Fab
*Anti-HIV Fab
-
**[[2pr4]], [[1dfb]], [[3piq]], [[3q6f]], [[3q6g]], [[4xml]], [[7mf7]], [[7mf8]], [[7mf9]], [[7mfa]], [[7mfb]] - hFab anti-HIV<br />
+
**[[2pr4]], [[1dfb]], [[3piq]], [[3q6f]], [[3q6g]], [[4d9l]], [[4xml]], [[5uby]], [[5ubz]], [[7mf7]], [[7mf8]], [[7mf9]], [[7mfa]], [[7mfb]], [[7ti6]] - hFab anti-HIV<br />
**[[3p30]], [[2xra]] – hFab 1281 anti-HIV + gp41 ectodomain<br />
**[[3p30]], [[2xra]] – hFab 1281 anti-HIV + gp41 ectodomain<br />
**[[3ngb]] – hFab anti-HIV + glycoprotein gp120 <br />
**[[3ngb]] – hFab anti-HIV + glycoprotein gp120 <br />
-
**[[6nc3]], [[6nc2]] – hFab anti-HIV + glycoprotein gp120 + glycoprotein gp41 – Cryo EM<br />
+
**[[8u1d]] – hFab anti-HIV + glycoprotein gp120 – Cryo EM <br />
 +
**[[6nc3]], [[6nc2]], [[8g4t]], [[8jtd]]– hFab anti-HIV + glycoprotein gp120 + glycoprotein gp41 – Cryo EM<br />
**[[3w9e]] – hFab anti-HIV 2 + glycoprotein D <br />
**[[3w9e]] – hFab anti-HIV 2 + glycoprotein D <br />
-
**[[7kde]] – hFab anti-HIV + HIV protein – Cryo EM<br />
+
**[[7kde]], [[7l86]], [[7l87]], [[7l88]], [[7l89]], [[7l8a]], [[7l8b]], [[7l8c]], [[7l8d]], [[7l8s]], [[7l8t]], [[7l8w]], [[7l8x]], [[7l8y]], [[7l8z]], [[7l90]] – hFab + HIV protein – Cryo EM<br />
-
**[[3cle]], [[3clf]], [[3cmo]], [[1h3p]], [[3oz9]], [[1mf2]], [[1nld]], [[1bog]], [[3mnv]], [[1il1]], [[7kkz]] - mFab anti-HIV<br />
+
**[[1u8h]], [[1u8i]], [[1u8j]], [[1u8l]], [[1u8k]], [[1u8m]], [[1u8n]], [[1u8o]], [[1u8p]], [[1u8q]], [[1u91]], [[1u92]], [[1u93]], [[1u95]], [[2p8l]], [[2p8m]], [[2p8p]], [[2pw1]], [[2pw2]], [[3idg]], [[3idi]], [[3idj]], [[3idm]], [[3idn]], [[3d0v]], [[3lex]], [[3ley]], [[4ydv]], [[6x58]] – hFab anti-HIV + gp41 peptide<br />
 +
**[[3mnz]] - hmFab anti-HIV + gp41 peptide<br />
 +
**[[2qsc]] - hFab anti-HIV + envelope glycoprotein peptide<br />
 +
**[[3uji]] - hFab anti-HIV + envelope glycoprotein gp160 peptide<br />
 +
**[[3mlr]], [[3mls]], [[3mlt]], [[3mlu]], [[3mlv]], [[3mlw]], [[3mlx]], [[3mly]], [[3mlz]] – hFab 2557 anti-HIV + V3 peptide<br />
 +
**[[1q1j]], [[3ujj]], [[4xmk]], [[6db5]], [[6db6]], [[6db7]] - hFab anti-HIV + glycoprotein gp120 peptide<br />
 +
**[[2hrp]] - hFab anti-HIV + HIV-1 protease peptide<br />
 +
**[[6o3u]] - hFab anti-HIV + PA<br />
 +
**[[4zto]] - rFab anti-HIV R53 + glycoprotein gp120 peptide - rabbit<br />
 +
**[[7mep]] - mrFab anti-HIV + glycoprotein gp120 – macaque – Cryo EM<br />
 +
**[[7mdt]], [[7mdu]] - mrFab anti-HIV + glycoprotein gp120 + gp41 – Cryo EM<br />
 +
**[[3cle]], [[3clf]], [[3cmo]], [[1h3p]], [[3oz9]], [[1mf2]], [[1nld]], [[1bog]], [[3mnv]], [[1il1]], [[5tr8]], [[7kkz]], [[9b44]] - mFab anti-HIV<br />
**[[1rzk]] – mFab anti-HIV + glycoprotein gp120 <br />
**[[1rzk]] – mFab anti-HIV + glycoprotein gp120 <br />
 +
**[[8fr6]] - mFab anti-HIV + glycoprotein gp120 + gp41 – Cryo EM<br />
**[[3mo1]] - hmFab anti-gp41<br />
**[[3mo1]] - hmFab anti-gp41<br />
-
**[[4ztp]] - rFab anti-HIV R53 - rabbit<br />
+
**[[3qq9]] - hmFab anti-RSV<br />
 +
**[[4ztp]] - rFab anti-HIV R53 <br />
**[[4jo1]], [[4jo2]], [[4jo3]], [[4jo4]] - rFab anti-HIV R56 + gp120 <br />
**[[4jo1]], [[4jo2]], [[4jo3]], [[4jo4]] - rFab anti-HIV R56 + gp120 <br />
-
**[[6did]] – rFab anti-HIV 10A + glycoprotein gp160 <br />
+
**[[6did]], [[6x96]], [[6x97]], [[6x98]] – rFab anti-HIV 10A + glycoprotein gp160 <br />
**[[6p62]] – rFab anti-HIV E70 + env NFL – Cryo EM<br />
**[[6p62]] – rFab anti-HIV E70 + env NFL – Cryo EM<br />
 +
 +
*Anti-SIV Fab
 +
 +
**[[8fbw]] - maFab anti-SIV + peptide<br />
 +
**[[3jcb]], [[3jcc]] - hFab + SIV gp120 + CD4 – CryoEM<br />
 +
**[[6tyb]] - mrFab + SIV gp160 + CD4 <br />
 +
**[[7t2p]], [[7t4g]] - mrFab + SIV gp120 + SIV gp41 – Cryo EM <br />
 +
**[[6tyb]] - mrFab + SIV gp160 + CD4 <br />
 +
 +
*Anti-CSP (circumsporozoite from malaria parasite) Fab
 +
 +
**[[5bk3]], [[5bk5]], [[6azx]], [[6b0w]], [[6e65]], [[6phg]], [[6phh]], [[7rqp]], [[8u70]] - hFab anti-CSP<br />
 +
**[[5bk0]], [[6axk]], [[6axl]], [[6azm]], [[6b0s]], [[6b5l]], [[6b5m]], [[6b5n]], [[6b5o]], [[6b5p]], [[6b5r]], [[6b5s]], [[6b5t]], [[6d11]], [[6d0x]], [[6d01]] [[6o23]], [[6o26]], [[6pbv]], [[6pbw]], [[6uc5]], [[6w05]], [[6wfx]], [[6wfy]], [[6wfz]], [[6wg0]], [[6wg1]], [[6wg2]], [[7k75]], [[7k76]], [[7lkb]], [[7lkg]], [[7raj]], [[7rcs]], [[7rd3]], [[7rd4]], [[7rd9]], [[7rda]], [[7rm0]], [[7rm1]], [[7rqq]], [[7rqr]], [[7sg5]], [[7sg6]], [[7sg6]], [[7ufn]], [[7ufo]], [[7ufq]], [[8fa9]] – hFab + CSP peptide<br />
 +
**[[6uud]], [[6x87]], [[6x8p]], [[6x8q]], [[6x8s]], [[6x8u]], [[7rlw]], [[7rlx]], [[7rly]], [[7rlz]], [[7rm3]], [[8f9e]], [[8f9t]], [[8f9u]], [[8f9v]], [[8f9w]], [[8fa6]], [[8fa7]], [[8fan]], [[8fat]], [[8fb5]], [[8fb7]], [[8fb8]], [[8fba]], [[8fdc]], [[8fdd]] – mFab + CSP peptide<br />
 +
**[[6e63]], [[6rcu]], [[6rcv]], [[6wn1]], [[7rxi]], [[7rxj]], [[7rxl]], [[7rxp]], [[7s0x]], [[7unb]], [[8fb6]] – hFab + CSP protein<br />
 +
**[[6mb3]], [[6mhg]], [[8ek1]], [[8eka]] – hFab + CSP protein – Cryo EM<br />
 +
**
 +
**[[6ohg]], [[6ule]], [[6x87]] – mFab + CSP – Cryo EM<br />
 +
**[[7rcs]], [[7rm3]], [[8f95]], [[8f9f]], [[8f9s]] – mFab + CSP peptide<br />
 +
**[[6w00]], [[6wfw]] – hFab + immunoglobulin G-binding protein + CSP peptide<br />
 +
**[[6o24]], [[6o25]], [[6o28]], [[6o29]], [[6o2a]], [[6o2b]], [[6o2c]], [[6ulf]], [[6vln]] – hFab + LgVHH + CSP<br />
 +
**[[8cdd]] – cFab + PFRCR complex – Cryo EM<br />
 +
**[[7jum]] – hscFv + P230<br />
 +
**[[7kjh]] – viVHH + P12p - vicuna<br />
 +
 +
*Anti-influenza virus Fab
 +
 +
**[[3qhz]], [[4fql]], [[4gxv]], [[6btj]], [[6dl8]], [[8vvb]] - hFab anti-influenza<br />
 +
**[[3qhf]] – hFab anti-influenza (mutant)<br />
 +
**[[6a0x]], [[8gv4]] - mFab anti-influenza virus<br />
 +
**[[8h3c]] – hFab + influenza peptide<br />
 +
**[[4n8c]] – mFab + influenza peptide<br />
 +
**[[4gxu]], [[4ubd]], [[5vag]], [[5w42]], [[5xrt]], [[6b3m]], [[6mlm]], [[6p3r]], [[6p3s]], [[6pdx]], [[6uig]], [[7tri]], [[8t1g]], [[8uwa]] – hFab + influenza virus hemagglutinin<br />
 +
**[[7mem]], [[7t3d]], [[7tz5]], [[8d21]], [[8tnl]], [[8toa]], [[8tp7]], [[8ut3]], [[8ut4]], [[8ut5]] – hFab + influenza virus hemagglutinin – Cryo EM<br />
 +
**[[8dg8]] – hFab + influenza virus glycoprotein – Cryo EM<br />
 +
**[[6lxi]], [[6lxj]], [[6lxk]] – hFab + influenza virus neuraminidase<br />
 +
**[[8ez3]], [[8ez8]] – hFab + influenza virus neuraminidase – Cryo EM<br />
 +
**[[8dg8]] – hFab + parainfluenza 3 virus F0 – Cryo EM<br />
 +
**[[4lvh]], [[1qfu]] – mFab anti-influenza haemagglutinin<br />
 +
**[[2aep]], [[2aeq]], [[1nma]], [[1nmb]], [[1nmc]] – mFab + influenza virus neuraminidase<br />
 +
**[[6j9o]], [[8jsb]] – hscFv anti-influenza<br />
 +
 +
*Anti-Ebola virus Fab
 +
 +
**[[3inu]], [[5vz1]], [[6b6z]], [[6dzn]], [[6n7u]], [[7rpt]] - hFab anti-ebola virus<br />
 +
**[[6dg2]] – mFab anti-Ebola<br />
 +
**[[6n7j]] - hFab anti-ebola + ebola peptide<br />
 +
**[[2qhr]] – mFab + Ebola envelope glycoprotein peptide<br />
 +
**[[6pci]], [[6dzl]], [[6dzm]], [[6uye]] – hFab + ebola spike proteins – Cryo EM<br />
 +
**[[6ea5]], [[6ea7]], [[6oz9]] – hFab + ebola glycoprotein<br />
 +
**[[8dpm]] – hFab + mscFv + ebola glycoproteins – Cryo EM<br />
* Other Fab
* Other Fab
Line 120: Line 221:
**[[6l8t]] - hmFab anti-hepatitis B<br />
**[[6l8t]] - hmFab anti-hepatitis B<br />
**[[2hwz]] – hmFab MEDI-493<br />
**[[2hwz]] – hmFab MEDI-493<br />
-
**[[6e64]] – raFab anti-malaria<br />
+
**[[8ef0]], [[8ef1]], [[8ef2]] - mrFab anti-Zika <br />
 +
**[[8sef]], [[8sgg]] – maFab anti-Epstein-Barr virus - macaca<br />
 +
**[[8eez]], [[8ef3]] - maFab anti-Zika <br />
 +
**[[6e64]] – rFab anti-malaria<br />
 +
**[[9f18]], [[9f1i]] – rFab anti-prostate antigen<br />
**[[4idl]] – LgFab anti-cholera toxin<br />
**[[4idl]] – LgFab anti-cholera toxin<br />
-
**[[1c5d]], [[1fn4]] – Fab anti-acetylcholine receptor - rat<br />
+
**[[1c5d]], [[1fn4]] – raFab anti-acetylcholine receptor - rat<br />
**[[6e8v]] – bFab-1<br />
**[[6e8v]] – bFab-1<br />
**[[6e9g]] – bFab-2<br />
**[[6e9g]] – bFab-2<br />
Line 130: Line 235:
**[[6e9q]] – bFab-6<br />
**[[6e9q]] – bFab-6<br />
**[[6e9u]] – bFab-7<br />
**[[6e9u]] – bFab-7<br />
 +
**[[8ctd]] – viVHH <br />
 +
**[[7tgf]], [[7tgi]], [[7th2]], [[7th3]] – viVHH + ricin<br />
 +
**[[8cds]] – viVHH anti-Nup93<br />
 +
**[[8ftg]] – lgVHH anti-caffeine<br />
*Fab: small molecule complex
*Fab: small molecule complex
 +
**[[8sjk]] - hFab + caffeine<br />
**[[3bpc]], [[2r1w]], [[2r1x]], [[2r1y]], [[2r23]], [[2r2b]], [[2r2e]], [[2r2h]], [[1m7d]] - mFab + liposaccharide<br />
**[[3bpc]], [[2r1w]], [[2r1x]], [[2r1y]], [[2r23]], [[2r2b]], [[2r2e]], [[2r2h]], [[1m7d]] - mFab + liposaccharide<br />
**[[3qcu]], [[3qcv]] - hFab LT3015 + phospholipid<br />
**[[3qcu]], [[3qcv]] - hFab LT3015 + phospholipid<br />
**[[1baf]] - mFab + hapten<br />
**[[1baf]] - mFab + hapten<br />
 +
**[[7u61]] – hFab anti-nicotine + nicotine<br />
**[[3l1o]] – mFab MN423 + Zn<br />
**[[3l1o]] – mFab MN423 + Zn<br />
**[[3i9g]] - mFab LT1009 + phospholipids<br />
**[[3i9g]] - mFab LT1009 + phospholipids<br />
Line 150: Line 261:
**[[2cju]], [[2uud]] – mFab anti-Phox + Phox-GABA<br />
**[[2cju]], [[2uud]] – mFab anti-Phox + Phox-GABA<br />
**[[2ddq]] - mFab + NHE-histidine<br />
**[[2ddq]] - mFab + NHE-histidine<br />
-
**[[1keg]] - mFab anti-photoproduct + DNA<br />
+
**[[1keg]], [[6kdi]] - mFab anti-photoproduct + DNA<br />
**[[5cp3]] – mFab anti-sulfonamide 4C7 + sulfonamide<br />
**[[5cp3]] – mFab anti-sulfonamide 4C7 + sulfonamide<br />
**[[6pyd]] - mFab anti-marinobufagenin + marinobufagenin <br />
**[[6pyd]] - mFab anti-marinobufagenin + marinobufagenin <br />
**[[6nfn]] - mFab anti-cocaine + benzoylecgonine<br />
**[[6nfn]] - mFab anti-cocaine + benzoylecgonine<br />
 +
**[[7u62]] - mFab anti-heroin + morphine<br />
 +
**[[7u64]], [[9axn]], [[9axo]] - mFab anti-fentanyl + fentanyl<br />
 +
**[[7u63]] - mFab anti-oxycodone + oxycodone<br />
*Fab: peptide complex
*Fab: peptide complex
Line 163: Line 277:
**[[6lra]] – hFab + tau peptide<br />
**[[6lra]] – hFab + tau peptide<br />
**[[7c94]] – hFab + podoplanin peptide<br />
**[[7c94]] – hFab + podoplanin peptide<br />
-
**[[6b5l]], [[6b5m]], [[6b5n]], [[6b5o]], [[6b5p]], [[6b5r]], [[6b5s]], [[6b5t]], [[6pbv]], [[6pbw]] – hFab + CSP peptide<br />
+
**[[5t6p]], [[5t78]], [[6kx1]] – hFab + MUC1 peptide<br />
-
**[[6n7j]] - hFab anti-ebola + ebola peptide<br />
+
**[[2osl]] – hmFab + CD20 peptide<br />
**[[2osl]] – hmFab + CD20 peptide<br />
**[[3o41]], [[3o45]] – mFab + fusion protein F1 peptide<br />
**[[3o41]], [[3o45]] – mFab + fusion protein F1 peptide<br />
Line 174: Line 287:
**[[2zpk]] – mFab + proteinase-activated receptor peptide<br />
**[[2zpk]] – mFab + proteinase-activated receptor peptide<br />
**[[3bae]], [[3bkj]], [[2r0w]], [[2r0z]], [[2ipu]] - mFab + amyloid peptide<br />
**[[3bae]], [[3bkj]], [[2r0w]], [[2r0z]], [[2ipu]] - mFab + amyloid peptide<br />
-
**[[2qhr]] – mFab + Ebola envelope glycoprotein peptide<br />
 
**[[1ejo]] - mFab + foot-and-mouth virus peptide<br />
**[[1ejo]] - mFab + foot-and-mouth virus peptide<br />
**[[2a6d]], [[2a6i]], [[2a6j]], [[2a6k]] – mFab 36-65 + peptide<br />
**[[2a6d]], [[2a6i]], [[2a6j]], [[2a6k]] – mFab 36-65 + peptide<br />
**[[3rkd]] - mFab + HEV-1 capsid peptide<br />
**[[3rkd]] - mFab + HEV-1 capsid peptide<br />
-
**[[1n64]], [[7lki]] - mFab + hepatitis C capsid peptide<br />
+
**[[1n64]], [[4hzl]], [[7lki]] - mFab + hepatitis C capsid peptide<br />
**[[1f90]] – mFab + IL-2 peptide<br />
**[[1f90]] – mFab + IL-2 peptide<br />
 +
**[[6p50]], [[6p67]] – mFab + IL-7<br />
 +
**[[7q4q]] – mFab + LRG1 peptide<br />
**[[2y06]], [[2y07]], [[2xzq]] – mFab + anti-Np murine germline peptide<br />
**[[2y06]], [[2y07]], [[2xzq]] – mFab + anti-Np murine germline peptide<br />
-
**[[2y36]], [[3uo1]], [[3uyr]], [[3v52]] – mFab + peptide<br />
+
**[[2y36]], [[3eyu]], [[3uo1]], [[3uyr]], [[3v52]], [[4qxt]], [[4qy8]], [[4qyo]], [[4r3s]], [[5mu2]] – mFab + peptide<br />
-
**[[3v4u]] - mFab + MHC-I antigen peptide<br />
+
**[[3v4u]], [[8hrh]] - mFab + MHC-I antigen peptide<br />
**[[1ktr]] – mFab + oligohistidine peptide<br />
**[[1ktr]] – mFab + oligohistidine peptide<br />
**[[1p4b]] – mFab + GCN4 peptide<br />
**[[1p4b]] – mFab + GCN4 peptide<br />
Line 189: Line 303:
**[[2or9]] - mFab anti-C-myc + peptide<br />
**[[2or9]] - mFab anti-C-myc + peptide<br />
**[[4tul]], [[4tuk]], [[4tuj]] – mFab anti-neuroblastoma + peptide<br />
**[[4tul]], [[4tuk]], [[4tuj]] – mFab anti-neuroblastoma + peptide<br />
-
**[[4n8c]] – mFab + influenza peptide<br />
+
**[[4bh7]], [[4bh8]] – mFab anti-ARS murine germline + peptide<br />
-
**[[4bh8]], [[4bh7]] – mFab anti-ARS murine germline + peptide<br />
+
**[[6sf6]] – mFab + COMP peptide<br />
**[[6sf6]] – mFab + COMP peptide<br />
**[[7doh]] – mFab + rhodopsin peptide<br />
**[[7doh]] – mFab + rhodopsin peptide<br />
-
**[[6uud]], [[6x87]], [[6x8p]], [[6x8q]], [[6x8s]], [[6x8u]] – mFab + CSP peptide<br />
+
**[[2g5b]] – mFab + Bax peptide<br />
-
**[[6lz4]] – raFab + MAP peptide<br />
+
**[[8g2m]] – mFab + masking peptide<br />
-
 
+
**[[6lz4]] – rFab + MAP peptide<br />
-
*Anti-HIV Fab: peptide complex
+
-
 
+
-
**[[3idg]], [[3idi]], [[3idj]], [[3idm]], [[3idn]], [[3d0v]], [[2pw1]], [[2pw2]], [[3lex]], [[3ley]], [[6x58]] – hFab anti-HIV + gp41 peptide<br />
+
-
**[[3mnz]] - hmFab anti-HIV + gp41 peptide<br />
+
-
**[[2qsc]] - hFab anti-HIV + envelope glycoprotein peptide<br />
+
-
**[[3uji]] - hFab anti-HIV + envelope glycoprotein gp160 peptide<br />
+
-
**[[3mlr]], [[3mls]], [[3mlt]], [[3mlu]], [[3mlv]], [[3mlw]], [[3mlx]], [[3mly]], [[3mlz]] – hFab 2557 anti-HIV + V3 peptide<br />
+
-
**[[1q1j]], [[3ujj]], [[4xmk]], [[6db5]], [[6db6]], [[6db7]] - hFab anti-HIV + glycoprotein gp120 peptide<br />
+
-
**[[2hrp]] - hFab anti-HIV + HIV-1 protease peptide<br />
+
-
**[[4zto]] - rFab anti-HIV R53 + glycoprotein gp120 peptide<br />
+
*Anti-SARS-CoV Fab
*Anti-SARS-CoV Fab
-
**[[7k3q]] - hFab anti-SARS <br />
+
**[[4oaw]], [[7k3q]], [[8f2v]] - hFab anti-SARS <br />
-
**[[7rnj]] - hFab anti-SARS + SARS spike peptide<br />
+
**[[7rnj]], [[8dtr]], [[8dtt]], [[8dtx]] - hFab anti-SARS + SARS spike peptide<br />
-
**[[2ghw]], [[6xe1]], [[6yla]], [[6ym0]], [[7bz5]], [[7dpm]], [[7e3o]], [[7jx3]], [[7k8v]], [[7k8w]], [[7l7d]], [[7l7e]], [[7m7w]], [[7n4i]], [[7n4j]], [[7nx6]], [[7nx7]], [[7nx8]], [[7nx9]], [[7nxa]], [[7nxb]], [[7r6w]], [[7r6x]] - hFab anti-SARS + SARS spike protein<br />
+
**[[2ghw]], [[5y11]], [[6xe1]], [[6yla]], [[6ym0]], [[7d6i]], [[7bz5]], [[7dpm]], [[7e3o]], [[7eam]], [[7ean]], [[7jx3]], [[7k8v]], [[7k8w]], [[7l7d]], [[7l7e]], [[7m7w]], [[7n4i]], [[7n4j]], [[7n4l]], [[7n4m]], [[7nab]], [[7nx6]], [[7nx7]], [[7nx8]], [[7nx9]], [[7nxa]], [[7nxb]], [[7r6w]], [[7r6x]], [[7sbu]], [[7t72]], [[7ul1]], [[7vzt]], [[7wqv]], [[7xsw]], [[7y3o]], [[7z0x]], [[7z0y]], [[8cwi]], [[8cwk]], [[8dnn]], [[8dw9]], [[8dwa]], [[8el2]], [[8eoo]], [[8e1g]], [[8f2t]], [[8f5i]], [[8hn6]], [[8hn7]], [[8sdf]], [[8sdg]] - hFab anti-SARS + SARS spike protein<br />
-
**[[6yor]], [[7akd]], [[7akj]], [[7cab]], [[7cac]], [[7cah]], [[7cai]], [[7cak]], [[7cwl]], [[7cwm]], [[7cwn]], [[7cwo]], [[7cyp]], [[7k8s]], [[7k8t]], [[7k8u]], [[7k8v]], [[7k8w]], [[7k8y]], [[7k8z]], [[7k90]], [[7ls9]], [[7lss]], [[7m42]], [[7n5h]], [[7p40]], ]]7phg]], [[7ra8]], [[7ral]] - hFab anti-SARS + SARS spike protein – Cryo EM<br />
+
**[[6yor]], [[7akd]], [[7akj]], [[7cab]], [[7cac]], [[7cah]], [[7cai]], [[7cak]], [[7cwl]], [[7cwm]], [[7cwn]], [[7cwo]], [[7cyp]], [[7k8s]], [[7k8t]], [[7k8u]], [[7k8v]], [[7k8w]], [[7k8y]], [[7k8z]], [[7k90]], [[7ls9]], [[7lss]], [[7m42]], [[7n5h]], [[7p40]], ]]7phg]], [[7q6e]], [[7qti]], [[7qtj]], [[7qtk]], [[7ra8]], [[7ral]], [[7s6k]], [[7s6l]], [[7u0p]], [[7u0q]], [[7u0x]], [[7ukm]], [[7uow]], [[7upl]], [[7wcd]], [[7wh8]], [[7whb]], [[7whd]], [[7wsa]], [[7x8w]], [[7x8y]], [[7x8z]], [[7x90]], [[7x91]], [[7x92]], [[7x93]], [[7x94]], [[7x95]], [[7xd2]], [[7y6l]], [[7y6n]], [[7y71]], [[7y72]], [[7yh6]], [[7yh7]], [[7ytn]], [[8c89]], [[8dpz]], [[8dxs]], [[8dzh]], [[8dzi]], [[8elj]], [[8err]], [[8f0g]], [[8fxb]], [[8gdr]], [[8h07]], [[8h08]], [[8hgl]], [[8hgm]], [[8jio]], [[8keh]], [[8q5y]], [[8qpr]], [[8qq0]], [[8r9w]], [[8tm1]], [[8tma]] - hFab anti-SARS + SARS spike protein – Cryo EM<br />
-
**[[7l0n]] - hFab anti-SARS + SARS spike protein + ACE<br />
+
**[[7v5j]], [[7v6o]], [[7x25]], [[7x28]], [[7x29]], [[7x2a]] - hFab anti-MERS + MERS spike protein – Cryo EM<br />
 +
**[[7l0n]] - hFab anti-SARS + SARS spike protein + ACE2<br />
 +
**[[8fxc]], [[8s9g]] - hFab anti-SARS + SARS spike protein + ACE2 – Cryo EM<br />
**[[7cr5]] - hFab anti-SARS + SARS nucleoprotein<br />
**[[7cr5]] - hFab anti-SARS + SARS nucleoprotein<br />
-
**[[3bgf]], [[4f2m]] – mFab + SARS spike protein<br />
+
**[[3bgf]], [[4f2m]], [[7uz6]], [[7uzc]], [[7uzd]], [[7wue]], [[8be1]] – mFab + SARS spike protein<br />
 +
**[[7dcc]], [[7dcx]], [[7dd2]], [[7dd8]], [[7dk4]], [[7dk5]], [[7dk6]], [[7dk7]], [[7u0q]], [[7uz4]], [[7uz5]], [[7uz7]], [[7uz8]], [[7uz9]], [[7uza]], [[7uzb]], [[7w9e]], [[7w9f]] - mFab anti-SARS + SARS spike protein – Cryo EM<br />
 +
**[[8fi9]], [[8tmy]] – mrFab + SARS spike peptide<br />
 +
**[[8fhy]], [[8gb5]] - maFab anti-SARS + SARS spike protein<br />
 +
**[[8der]] - maFab anti-SARS + SARS spike protein – Cryo EM<br />
**[[7m53]] – mFab + SARS spike peptide<br />
**[[7m53]] – mFab + SARS spike peptide<br />
**[[7deo]], [[7det]], [[7deu]] – mscFv + SARS spike protein<br />
**[[7deo]], [[7det]], [[7deu]] – mscFv + SARS spike protein<br />
 +
**[[8wfm]] – SARSscFv + SARS spike protein<br />
 +
**[[8juh]] – sscFv + SARS spike protein<br />
 +
**[[8gzz]], [[8h00]], [[8h01]], [[8heb]], [[8hec]], [[8itu]] - rFab anti-SARS + SARS spike protein – Cryo EM<br />
*Human Fab: protein complex
*Human Fab: protein complex
-
**[[3ux9]], [[4z5r]]– hFab anti-interferon + interferon<br />
+
**[[3ux9]], [[4ypg]], [[4z5r]]– hFab anti-interferon + interferon<br />
**[[2nyy]], [[2nz9]] – hFab + botulinum neurotoxin<br />
**[[2nyy]], [[2nz9]] – hFab + botulinum neurotoxin<br />
**[[3w2d]] – hFab + enterotoxin<br />
**[[3w2d]] – hFab + enterotoxin<br />
**[[7ce2]] – hFab + tetanus toxin<br />
**[[7ce2]] – hFab + tetanus toxin<br />
 +
**[[7oh0]], [[7oh1]] – hFab + tetanus toxin – Cryo EM<br />
**[[4mxv]] – hFab anti-lymphotoxin-α + lymphotoxin-α<br />
**[[4mxv]] – hFab anti-lymphotoxin-α + lymphotoxin-α<br />
**[[2ybr]], [[2yc1]] – hFab + scorpion toxin<br />
**[[2ybr]], [[2yc1]] – hFab + scorpion toxin<br />
 +
**[[7so5]], [[7so7]] - hFab + toxin B<br />
**[[2r4r]], [[2r4s]] – hFab + adrenergic receptor<br />
**[[2r4r]], [[2r4s]] – hFab + adrenergic receptor<br />
**[[4hj0]] – hFab + GIP receptor<br />
**[[4hj0]] – hFab + GIP receptor<br />
Line 234: Line 348:
**[[2xqb]], [[4g6j]], [[4g6m]] - hFab + interleukin<br />
**[[2xqb]], [[4g6j]], [[4g6m]] - hFab + interleukin<br />
**[[1s78]] - hFab commercial + ERBB-2<br />
**[[1s78]] - hFab commercial + ERBB-2<br />
-
**[[3hmx]] - hFab commercial + IL-12<br />
+
**[[3hmx]] - hFab commercial + 12<br />
**[[6wzm]] – hFab + IL-8<br />
**[[6wzm]] – hFab + IL-8<br />
 +
**[[4hwb]], [[4hwe]] – hFab + IL-13<br />
**[[6u6u]] - hFab + IL-36R<br />
**[[6u6u]] - hFab + IL-36R<br />
**[[3eoa]], [[3eob]] - hFab commercial + integrin<br />
**[[3eoa]], [[3eob]] - hFab commercial + integrin<br />
Line 246: Line 361:
**[[4k7p]] – hFab RHUMAB6 + mFab 10C4<br />
**[[4k7p]] – hFab RHUMAB6 + mFab 10C4<br />
**[[5xf1]], [[5xez]] – hFab + glucagon receptor<br />
**[[5xf1]], [[5xez]] – hFab + glucagon receptor<br />
-
**[[4hj0]], [[6jbt]], [[6k0y]], [[7bxa]] – hFab + PD-1<br />
+
**[[4hj0]], [[5grj]], [[6jbt]], [[6jjp]], [[6k0y]], [[7bxa]], [[7cgw]], [[7wvm]] – hFab + PD-1<br />
**[[6wzj]], [[6wzk]], [[6wzl]] - hFab + chemokine<br />
**[[6wzj]], [[6wzk]], [[6wzl]] - hFab + chemokine<br />
 +
**[[8a44]] - hFab + chemokine receptor + duffy binding protein<br />
**[[6a3w]] - hFab + TNFR 9<br />
**[[6a3w]] - hFab + TNFR 9<br />
**[[6rps]] - hFab + carbonic anhydrase<br />
**[[6rps]] - hFab + carbonic anhydrase<br />
**[[6r2s]] – hFab + duffy receptor<br />
**[[6r2s]] – hFab + duffy receptor<br />
**[[6al5]] - hFab anti-CD19 + CD19<br />
**[[6al5]] - hFab anti-CD19 + CD19<br />
-
**[[6vja]] – hFab + CD20 – Cryo EM<br />
+
**[[7uic]] - hFab + CD19 + CD81<br />
 +
**[[6vja]], [[6y92]], [[6y97]], [[6y9a]] – hFab + CD20 – Cryo EM<br />
 +
**[[7o52]] - hFab anti-CD22 + CD22<br />
 +
**[[7dha]], [[7duo]] - hFab anti-CD38 + CD38<br />
 +
**[[5tz2]], [[5tzt]], [[5tzu]], [[7wn8]] - hFab anti-CD47 + CD47<br />
**[[6aod]] - hFab + coagulation factor XI<br />
**[[6aod]] - hFab + coagulation factor XI<br />
**[[6ss2]], [[6ss4]], [[6ss6]] - hFab + arginase<br />
**[[6ss2]], [[6ss4]], [[6ss6]] - hFab + arginase<br />
 +
**[[7lex]], [[7ley]], [[7lez]], [[7lf0]], [[7lf1]], [[7lf2]] - hFab + arginase – Cryo EM<br />
 +
**[[7mpg]] - hFab + fusion glycoprotein – Cryo EM<br />
 +
**[[7nbx]], [[7ncs]], [[7nd0]] - hFab + BAM complex – Cryo EM<br />
**[[6s5a]] – hFab + LALA<br />
**[[6s5a]] – hFab + LALA<br />
**[[6w7s]], [[6wh9]] – hFab + KR1<br />
**[[6w7s]], [[6wh9]] – hFab + KR1<br />
-
**[[6e63]], [[6rcu]], [[6rcv]], [[6wn1]] – hFab + CSP protein<br />
 
-
**[[6mb3]], [[6mhg]] – hFab + CSP protein – Cryo EM<br />
 
**[[6umx]] - hFab + growth factor 8<br />
**[[6umx]] - hFab + growth factor 8<br />
**[[6umg]] - hFab + CGRP receptor<br />
**[[6umg]] - hFab + CGRP receptor<br />
 +
**[[5ngv]], [[5nh3]] - hFab + activin receptor<br />
**[[6bfq]], [[6bfs]] – hFab + GM-CSF<br />
**[[6bfq]], [[6bfs]] – hFab + GM-CSF<br />
**[[6bit]] – hFab + SIRP-alpha<br />
**[[6bit]] – hFab + SIRP-alpha<br />
**[[6t9e]] - hFab + platelet factor B<br />
**[[6t9e]] - hFab + platelet factor B<br />
**[[6t9d]] - hFab + VEGF<br />
**[[6t9d]] - hFab + VEGF<br />
 +
**[[7o4y]] - hFab + anti-kappa VHH<br />
 +
**[[6fgb]] – hFab + FcRn<br />
 +
**[[7sht]], [[7shu]], [[7shy]], [[7shz]] – hFab + IgE-Fc<br />
 +
**[[7mn8]] – hFab + HER2 + HER3 + NRG1b – Cryo EM<br />
 +
**[[7v5n]] – hFab + DNA<br />
 +
**[[7eow]] – hVHH + von Willenbrand factor<br />
 +
**[[5l0q]], [[8gh4]] – hFab + ADAM10<br />
 +
**[[7jwg]], [[8tuz]] – hFab + OspA<br />
 +
**[[4hjg]], [[4ioi]] – hFab + immunoglobulin G-binding protein + protein L peptide<br />
 +
**[[5i5k]] – hFab + complement C6<br />
 +
**[[8f60]], [[8f6l]], [[8f6o]] - hFab + BTLA<br />
 +
**[[8sr0]] - hFab + LAG3<br />
 +
**[[8so3]] - hFab + LAG3 – Cryo EM<br />
 +
**[[8f6l]] - hFab + BTLA<br />
 +
**[[7zqt]] - hFab + nanobody + adhesin<br />
 +
**[[8b7h]] - hFab + gremlin-1<br />
 +
**[[8jel]], [[8jen]], [[8jeo]] - hFab anti-TIGIT+ T-cell immunoreceptor<br />
 +
**[[8vdf]], [[8vdg]], [[9bhb]] - hFab + erythrocyte membrane protein – Cryo EM<br />
 +
**[[8dfg]], [[8dfh]], [[8dfi]] - hFab + merozoite surface protein<br />
 +
**[[8aon]] - hmFab anti-QSOX1+ QSOX1<br />
 +
**[[8bk2]] - hFab + factor H binding protein<br />
 +
**[[8e7m]] - hFab + ACE2 – Cryo EM<br />
 +
**[[8ghp]] - hFab + guanylyl cyclase<br />
 +
**[[8cyh]] – hFab + mesothelin<br />
 +
**[[8tgp]] – hFab + VISTA<br />
 +
**[[8jyq]] – hmFab + HER2 peptide<br />
*Human Fab: viral protein complex
*Human Fab: viral protein complex
Line 271: Line 419:
**[[6iw0]], [[6iw2]], [[6ivz]] – hFab + yellow fever E protein <br />
**[[6iw0]], [[6iw2]], [[6ivz]] – hFab + yellow fever E protein <br />
**[[3iyw]] – hFab mAb + West Nile virus surface protein<br />
**[[3iyw]] – hFab mAb + West Nile virus surface protein<br />
-
**[[4ubd]], [[5vag]], [[6mlm]], [[6p3s]], [[6pdx]], [[6uig]] – hFab + influenza virus hemagglutinin<br />
+
**[[7dwt]], [[7dwu]], [[8fe3]], [[8fe4]], [[8jn1]], [[8jn3]], [[8jn6]] – hFab + Dengue envelope glycoprotein – Cryo EM<br />
-
**[[6lxi]], [[6lxj]] – hFab + influenza virus neuraminidase<br />
+
-
**[[2ghw]], [[6xe1]], [[6ym0]], [[7bz5]], [[7jx3]], [[7k8v]], [[7k8w]] - hFab anti-SARS + SARS spike protein<br />
+
-
**[[7cac]], [[7cah]], [[7cai]], [[7cak]], [[7k8s]], [[7k8t]], [[7k8u]], [[7k8z]], [[7ls9]], [[7lss]] - hFab anti-SARS + SARS spike protein – Cryo EM<br />
+
-
**[[7l0n]] - hFab anti-SARS + SARS spike protein + ACE<br />
+
-
**[[7cr5]] - hFab anti-SARS + SARS nucleoprotein<br />
+
-
**[[7dwt]], [[7dwu]] – hFab + Dengue envelope glycoprotein – Cryo EM<br />
+
**[[6weq]], [[6wer]] – hFab + dengue virus NS1c <br />
**[[6weq]], [[6wer]] – hFab + dengue virus NS1c <br />
**[[6cmg]], [[6cmi]] – hFab + Hendra virus glycoprotein <br />
**[[6cmg]], [[6cmi]] – hFab + Hendra virus glycoprotein <br />
**[[6bp2]] – hFab + Marburg virus glycoprotein <br />
**[[6bp2]] – hFab + Marburg virus glycoprotein <br />
 +
**[[7rfb]], [[7rfc]] – hFab + Hepatitis C virus glycoprotein <br />
 +
**[[8tgz]], [[8u9y]] – hFab + Hepatitis C virus glycoprotein – Cryo EM<br />
 +
**[[7sgf]], [[9cj7]] – hFab + Lassa virus glycoprotein – Cryo EM<br />
 +
**[[5wna]], [[5wnb]] – hFab + Human respiratory syncytial virus glycoprotein <br />
 +
**[[5wn9]] – hscFv + Human respiratory syncytial virus glycoprotein <br />
**[[6txz]] – hFab + Hepatitis A virus protein<br />
**[[6txz]] – hFab + Hepatitis A virus protein<br />
-
**[[6ieb]], [[6iec]], [[6iek]] – hFab + Rift Valley fever virus protein<br />
+
**[[6iea]], [[6ieb]], [[6iec]], [[6iek]] – hFab + Rift Valley fever virus protein<br />
-
**[[6w09]] – hFab + Chikungunya glycoproteins – Cryo EM<br />
+
**[[6w09]], [[7cvz]], [[7cvy]], [[7cw0]], [[7cw2]], [[7cw3]] – hFab + Chikungunya glycoproteins – Cryo EM<br />
**[[6w1c]] – hFab + Mayaro virus glycoproteins – Cryo EM<br />
**[[6w1c]] – hFab + Mayaro virus glycoproteins – Cryo EM<br />
**[[6vyv]] – hFab + Ross River virus glycoproteins – Cryo EM<br />
**[[6vyv]] – hFab + Ross River virus glycoproteins – Cryo EM<br />
-
**[[6dfi]], [[6dfj]], [[6jep]], [[6jfh]], [[6jfi]], [[7bpk]] – hFab + zika protein <br />
+
**[[6dfi]], [[6dfj]], [[6jep]], [[6jfh]], [[6jfi]], [[7a3n]], [[7a3u]], [[7bpk]], [[7bq5]] – hFab + zika protein <br />
 +
**[[7t17]] – hFab + zika protein – Cryo EM<br />
 +
**[[8dmh]] - hFab + Lymphocytic choriomeningitis glycoprotein – Cryo EM<br />
**[[6uoe]] – hFab + herpesvirus protein<br />
**[[6uoe]] – hFab + herpesvirus protein<br />
-
**[[6pci]], [[6dzm]], [[6uye]] – hFab + ebola spike proteins – Cryo EM<br />
+
**[[7yrn]] – hFab + herpesvirus protein – Cryo EM<br />
-
**[[6oz9]] – hFab + ebola glycoprotein<br />
+
**[[8r9x]],
 +
**[[7cn2]] – hFab + papilloma virus capsid – Cryo EM<br />
 +
**[[6wm9]], [[6wn1]], [[6wno]], [[6woz]], [[6wqo]], [[6wtu]], [[6wtv]], [[6wty]], [[7phu]], [[8pwu]], [[8pwv]] - hFab + reticulocyte binding protein<br />
 +
**[[6ous]], [[7mmn]] – hFab + HRSV protein<br />
 +
**[[6wds]], [[6wdt]] – hFab + enterovirus glycoproteins – Cryo EM<br />
 +
**[[6h2y]] – hFab + Neisseria lipoprotein<br />
 +
**[[7ur4]], [[8f6x]] – hFab + metapneumovirus glycoprotein F0 – Cryo EM<br />
 +
**[[8k3c]], [[8xps]], [[8xpy]] – hFab + Nipah virus glycoprotein – Cryo EM<br />
 +
**[[8wsp]] – hFab + SFTS virus glycoprotein <br />
 +
**[[8r9y]], [[8r9z]] – hFab + porcine deltacoronavirus protein – Cryo EM<br />
 +
 
 +
*Mouse Fab: peptide complex
 +
 
 +
**[[8duz]] – mFab + gonococcal lipooligosaccharide peptide<br />
 +
**[[7t0l]] – mFab + MHC-I antigen + beta-2-microglobulin + peptide<br />
 +
**[[3sge]] – mFab + R13 peptide <br />
 +
**[[3eys]] – mFab + peptide <br />
 +
**[[3e8u]] – mFab + BNP peptide<br />
*Mouse Fab: protein complex
*Mouse Fab: protein complex
Line 296: Line 462:
**[[3ncy]] – mFab + arginine agmatine antiporter<br />
**[[3ncy]] – mFab + arginine agmatine antiporter<br />
**[[2zch]], [[2zcl]] – mFab 8G8F5 + PSA<br />
**[[2zch]], [[2zcl]] – mFab 8G8F5 + PSA<br />
-
**[[2vc2]], [[2vdk]], [[2vdl]], [[2vdm]], [[2vdn]], [[5hdb]] - mFab + integrin<br
+
**[[2vc2]], [[2vdk]], [[2vdl]], [[2vdm]], [[2vdn]], [[4o02]], [[5hdb]] - mFab + integrin<br />
 +
**[[7la4]] - mFab + integrin – Cryo EM<br />
**[[3kj6]] – mFab + β-2 adrenoreceptor<br />
**[[3kj6]] – mFab + β-2 adrenoreceptor<br />
-
**[[3d9a]], [[1bql]], [[1fbi]], [[2iff]], [[1fdl]], [[3hfm]], [[1c08]], [[1dqj]], [[1nby]], [[1nbz]], [[1ndg]], [[1ndm]], [[1p2c]], [[1ua6]], [[1uac]], [[1xgp]], [[1xgq]], [[1yqv]], [[1mlc]], [[1kip]], [[1kiq]], [[1kir]] – mFab HYHEL + lysozyme<br />
+
**[[3d9a]], [[1bql]], [[1fbi]], [[2iff]], [[1fdl]], [[3hfm]], [[1c08]], [[1dqj]], [[1nby]], [[1nbz]], [[1ndg]], [[1ndm]], [[1p2c]], [[1ua6]], [[1uac]], [[1xgp]], [[1xgq]], [[1yqv]], [[1mlc]], [[1kip]], [[1kiq]], [[1kir]], [[8gq1]] – mFab HYHEL + lysozyme<br />
**[[1ic4]], [[1ic5]], [[1ic7]], [[1j1p]], [[1j1o]], [[1j1x]], [[2dqc]], [[2dqd]], [[2dqe]], [[2dqf]], [[2dqg]], [[2dqh]], [[2dqi]], [[2dqj]], [[3a67]], [[3a6b]], [[3a6c]] - mFab HYHEL10 (mutant) + lysozyme<br />
**[[1ic4]], [[1ic5]], [[1ic7]], [[1j1p]], [[1j1o]], [[1j1x]], [[2dqc]], [[2dqd]], [[2dqe]], [[2dqf]], [[2dqg]], [[2dqh]], [[2dqi]], [[2dqj]], [[3a67]], [[3a6b]], [[3a6c]] - mFab HYHEL10 (mutant) + lysozyme<br />
**[[4aei]] - mFab anti-AAHI + scorpion toxin<br />
**[[4aei]] - mFab anti-AAHI + scorpion toxin<br />
 +
**[[4rgm]], [[4rgn]], [[4rgo]] – mFab + enterotoxin<br />
**[[4ag4]] - mFab + DDR1<br />
**[[4ag4]] - mFab + DDR1<br />
**[[4f37]] – mFab anti-amyloid-β + colicin E7<br />
**[[4f37]] – mFab anti-amyloid-β + colicin E7<br />
Line 312: Line 480:
**[[1wej]] – mFab E8 + cytochrome C<br />
**[[1wej]] – mFab E8 + cytochrome C<br />
**[[2j4w]], [[2j5l]] – mFab + apical membrane antigen<br />
**[[2j4w]], [[2j5l]] – mFab + apical membrane antigen<br />
-
**[[2nr6]], [[5vyf]] – mFab + allergen <br />
+
**[[2nr6]], [[5vcn]], [[5vco]], [[5vyf]] – mFab + allergen <br />
**[[2hlf]], [[2ht2]], [[2ht3]], [[2ht4]], [[2htk]], [[2htl]], [[2h2p]], [[2h2s]], [[2exw]], [[2exy]], [[2fee]], [[1ots]] – mFab + exchange transporter ClCA<br />
**[[2hlf]], [[2ht2]], [[2ht3]], [[2ht4]], [[2htk]], [[2htl]], [[2h2p]], [[2h2s]], [[2exw]], [[2exy]], [[2fee]], [[1ots]] – mFab + exchange transporter ClCA<br />
**[[7kgv]] – mFab + neutral amino acid transporter<br />
**[[7kgv]] – mFab + neutral amino acid transporter<br />
Line 320: Line 488:
**[[1ymh]] – mFab + protein L (mutant)<br />
**[[1ymh]] – mFab + protein L (mutant)<br />
**[[1v7m]], [[1v7n]] – mFab TN1 + thrombopoietin<br />
**[[1v7m]], [[1v7n]] – mFab TN1 + thrombopoietin<br />
 +
**[[8uf7]] – mFab + thrombin – Cryo EM<br />
 +
**[[8jf7]] – mFab + glutamate receptor – Cryo EM<br />
 +
**[[9ima]] – mFab + GPRC5D – Cryo EM<br />
**[[1fsk]] - mFab + pollen allergen<br />
**[[1fsk]] - mFab + pollen allergen<br />
**[[1keg]], [[1ehl]] – mFab + DNA<br />
**[[1keg]], [[1ehl]] – mFab + DNA<br />
 +
**[[7xlt]] – mFab + RNA:DNA – Cryo EM<br />
**[[3liz]] – mFab 4C3 + aspartic protease<br />
**[[3liz]] – mFab 4C3 + aspartic protease<br />
**[[3nid]], [[3nif]], [[3nig]], [[3t3m]], [[3t3p]], [[3v4p]], [[3v4v]] – mFab 10E5 + integrin<br />
**[[3nid]], [[3nif]], [[3nig]], [[3t3m]], [[3t3p]], [[3v4p]], [[3v4v]] – mFab 10E5 + integrin<br />
 +
**[[7l8p]] – mFab 10E5 + integrin + drug<br />
**[[3v6o]] – mFab + leptin receptor<br />
**[[3v6o]] – mFab + leptin receptor<br />
**[[5tr1]], [[5tqq]] - mFab + Cl channel<br />
**[[5tr1]], [[5tqq]] - mFab + Cl channel<br />
Line 330: Line 503:
**[[5dlm]] - mFab + matrix protein 2<br />
**[[5dlm]] - mFab + matrix protein 2<br />
**[[4zyp]] – mFab + fusion protein F0<br />
**[[4zyp]] – mFab + fusion protein F0<br />
-
**[[6a77]], [[6a78]] - mFab anti-ROBO1 + roundabout homolog<br />
+
**[[3wih]], [[6a77]], [[6a78]] - mFab anti-ROBO1 + roundabout homolog<br />
**[[6a79]] - mFab anti-ROBO1 (mutant) + roundabout homolog<br />
**[[6a79]] - mFab anti-ROBO1 (mutant) + roundabout homolog<br />
**[[7jti]] – mFab + retinol-binding protein<br />
**[[7jti]] – mFab + retinol-binding protein<br />
**[[6mlk]] – mFab + DEBS<br />
**[[6mlk]] – mFab + DEBS<br />
-
**[[6cxy]], [[6vel]] – mFab + cadherin<br />
+
**[[6cxy]], [[6vel]], [[7stz]] – mFab + cadherin<br />
-
**[[6hx4]] – mFab + antitrypsin<br />
+
**[[6i3z]], [[6hx4]] – mFab + antitrypsin<br />
**[[6nex]] – mFab anti-cocaine + ighg<br />
**[[6nex]] – mFab anti-cocaine + ighg<br />
-
**[[7a65]], [[7a69]], [[7a6c]], [[7a6e]], [[7a6f]] – mFab + ABCB + drug – Cryo EM<br />
+
**[[7a65]], [[7a69]], [[7a6c]], [[7a6e]], [[7a6f]], [[7neq]], [[7nez]], [[7nfd]] – mFab + ABCB + drug – Cryo EM<br />
-
**[[6ohg]] – mFab + P230<br />
+
**[[6rnn]], [[6s3t]] – mFab + mycoplasma surface protein<br />
 +
**[[7jgj]] - mFab + immunoglobulin protease – Cryo EM<br />
 +
**[[6z2l]] – mFab + P113<br />
 +
**[[1sy6]] – mFab + CD3 <br />
 +
**[[3ubx]] – mFab + CD1d + beta-2-microglobulin <br />
 +
**[[6lyn]] – mFab + CD146 <br />
 +
**[[5x0t]], [[5x4g]] – mFab + CD147 <br />
 +
**[[7zwi], [[7zwm]], [[7zxf]], [[7zxg]] – mFab + P45/48<br />
 +
**[[4okv]] – mFab + anti-platelet aggregation protein <br />
 +
**[[3opz]] – mFab + sialidase <br />
 +
**[[5hdq]] – mFab + MntC <br />
 +
**[[4kuc]] – mFab + ricin<br />
 +
**[[3u9u]] – mFab + Erbb4<br />
 +
**[[5c0n]], [[5d8j]] – mFab + fatty-acid binding protein<br />
 +
**[[5vlp]] – mFab + convertase + LDLR peptide<br />
 +
**[[7q6c]] – mFab + lgVHH + complement C6<br />
 +
**[[6y90]] – mFab + CD20 – Cryo EM<br />
 +
**[[5xbm]] – mFab + Scarb2<br />
 +
**[[4edx]] - mFab + nerve growth factor<br />
 +
**[[7txw]] – mFab + p25<br />
 +
**[[5e8d]] – mFab + epiregulin<br />
 +
**[[7zmk]] - mFab + microfibril-associated glycoprotein<br />
 +
**[[1a2y]] – mFab D1.3 + lysozyme<br />
 +
**[[7zwi]], [[7zxg]] – mFab + malaria surface protein<br />
 +
**[[8yxi]] – mFab + Rift Valley fever virus protein<br />
 +
**[[8ukh]], [[8ulf]] – mFab + CELTOS<br />
 +
**[[7wg3]] – mFab + IL-17R<br />
 +
**[[8tfn]] – mFab + TCR<br />
 +
**[[8jyr]] – mFab + HER2 <br />
 +
**[[8w9j]] – mFab + CLEC12A <br />
 +
**[[8jlw]], [[8jlx]] – mFab anti-hemorrhagic fever virus + glycoprotein – Cryo EM<br />
 +
**[[8onk]] – mFab + insulin <br />
*Mouse Fab: viral protein complex
*Mouse Fab: viral protein complex
-
**[[4lvh]], [[1qfu]] – mFab anti-influenza haemagglutinin<br />
 
-
**[[2aep]], [[2aeq]], [[1nma]], [[1nmb]], [[1nmc]] – mFab + influenza virus neuraminidase<br />
 
**[[3i50]], [[1ztx]] – mFab E53 + West Nile virus envelope glycoprotein<br />
**[[3i50]], [[1ztx]] – mFab E53 + West Nile virus envelope glycoprotein<br />
-
**[[2r29]], [[4l5f]] – mFab + Dengue envelope glycoprotein<br />
+
**[[2r29]], [[3uyp]], [[3uze]], [[3uzq]], [[3uzv]], [[4l5f]] – mFab + Dengue envelope glycoprotein<br />
 +
**[[8fe3]], [[8fe4]] – mFab + Dengue envelope glycoprotein + Prm protein – Cryo EM<br />
**[[3fmg]] - mFab 4F8 + Simian rotavirus glycoprotein VP7<br />
**[[3fmg]] - mFab 4F8 + Simian rotavirus glycoprotein VP7<br />
**[[3j1s]], [[6ewb]] – mFab + Vp1<br />
**[[3j1s]], [[6ewb]] – mFab + Vp1<br />
**[[2xqy]] - mFab anti-pseudorabies virus + glycoprotein H <br />
**[[2xqy]] - mFab anti-pseudorabies virus + glycoprotein H <br />
-
**[[3bgf]], [[4f2m]] – mFab + SARS spike protein<br />
+
**[[3v7a]], [[7l5j]] - mFab + norovirus capsid protein<br />
-
**[[3v7a]] - mFab + norovirus capsid protein<br />
+
**[[6l62]] - mFab + circovirus capsid protein – Cryo EM<br />
**[[6l62]] - mFab + circovirus capsid protein – Cryo EM<br />
 +
**[[5mhr]] - mFab + reoovirus sigma 1 <br />
 +
**[[4q0x]], [[5vxr]] - mFab + hepatitis C ivirus peptide<br />
 +
**[[6q0b]] - mFab + polioovirus capsid proteins – Cryo EM<br />
**[[2i9l]] – mFab + vaccinia virus protein<br />
**[[2i9l]] – mFab + vaccinia virus protein<br />
 +
**[[5eor]], [[5eoq]] – mFab + vaccinia virus protein A27 peptide<br />
**[[4etq]] – mFab anti-vaccinia + IMV membrane protein<br />
**[[4etq]] – mFab anti-vaccinia + IMV membrane protein<br />
**[[6j5d]] - mFab + louping ILL virus protein – cryo EM<br />
**[[6j5d]] - mFab + louping ILL virus protein – cryo EM<br />
Line 358: Line 564:
**[[6uvo]] – mFab + HRSV protein<br />
**[[6uvo]] – mFab + HRSV protein<br />
**[[6cxc]] – mFab + HRSV protein – Cryo EM<br />
**[[6cxc]] – mFab + HRSV protein – Cryo EM<br />
-
**[[6tys]] – mFab + Nipah virus glycoprotein – Cryo EM<br />
+
**[[6tys]], [[8dmj]] – mFab + Nipah virus glycoprotein – Cryo EM<br />
 +
**[[8ja5]] – mFab + Nipah virus glycoprotein <br />
 +
**[[6vy5]], [[6vy6]] – mFab + Nipah virus RBP<br />
**[[7ebr]], [[7ebz]], [[7ec5]], [[7ecy]] – mFab + enterovirus glycoproteins – Cryo EM<br />
**[[7ebr]], [[7ebz]], [[7ec5]], [[7ecy]] – mFab + enterovirus glycoproteins – Cryo EM<br />
 +
**[[7syy]], [[7syz]], [[8jr3]] – mFab + Hendra virus glycoprotein<br />
 +
**[[7ki4]], [[7ki6]] – mFab + Hendra virus glycoprotein – Cryo EM<br />
 +
**[[7m51]], [[7m52]], [[7m55]] – mFab + MERS spike peptide<br />
 +
**[[8too]] – mFab anti-Epstein-Barr virus + glycoprotein p42<br />
*Other Fab: protein complex
*Other Fab: protein complex
Line 367: Line 579:
**[[1l7i]] - hmFab + ERBB-2<br />
**[[1l7i]] - hmFab + ERBB-2<br />
**[[1bj1]], [[2vwe]] - hmFab + VEGF<br />
**[[1bj1]], [[2vwe]] - hmFab + VEGF<br />
 +
**[[4gw1]], [[4gw5]] - hmFab + CQFD meditop<br />
 +
**[[5jq6]] - hmFab + ClfA<br />
 +
**[[4edw]] - hmFab + nerve growth factor<br />
**[[3uaj]], [[3uc0]] – Fab + envelope protein - chimpanzee<br />
**[[3uaj]], [[3uc0]] – Fab + envelope protein - chimpanzee<br />
 +
**[[8ee5]], [[8ee8]], [[8eed]], [[8eee]] – mrFab + Zika virus glycoprotein<br />
 +
**[[8sgn]], [[8sm1]], [[8tnn]] – maFab anti-Epstein-Barr virus + glycoprotein<br />
 +
**[[8k0c]] – maFab anti-Epstein-Barr virus + glycoprotein – Cryo EM<br />
 +
**[[8k0d]] – maFab anti-Nipah virus + glycoprotein – Cryo EM<br />
 +
**[[8tmz]] – maFab + MERS spike peptide<br />
 +
**[[8sak]] – maFab + MERS spike protein – Cryo EM<br />
 +
**[[8deq]] - maFab + equine encephalitis virus protein – Cryo EM<br />
**[[3b9k]] – rFab + CD8<br />
**[[3b9k]] – rFab + CD8<br />
**[[6i9i]] – rFab + Rift Valley fever virus glycoprotein<br />
**[[6i9i]] – rFab + Rift Valley fever virus glycoprotein<br />
**[[6t3f]] – rFab + Nipah virus glycoprotein<br />
**[[6t3f]] – rFab + Nipah virus glycoprotein<br />
**[[6osh]], [[6osn]], [[6osv]] – rFab + ROR2<br />
**[[6osh]], [[6osn]], [[6osv]] – rFab + ROR2<br />
 +
**[[6e62]] – rFab + Pf48/45<br />
 +
**[[8kei]] – rFab + cytochrome B-245 – Cryo EM<br />
**[[6h5n]] – raFab + malaria protein<br />
**[[6h5n]] – raFab + malaria protein<br />
**[[6zvf]] – raFab + galectin<br />
**[[6zvf]] – raFab + galectin<br />
 +
**[[5nh3]] - raFab + activin receptor<br />
 +
**[[7yru]] – raFab + zinc metalloproteinase<br />
 +
**[[4d3c]] - raFab + hepatocyte growth factor<br />
**[[6icc]], [[6icf]] – raFab + S2P<br />
**[[6icc]], [[6icf]] – raFab + S2P<br />
-
**[[7b09]] - vFab + hantavirus envelope polyprotein – vole - Cryo EM<br />
+
**[[8xxo]] – raFab + IGE<br />
-
**[[6tyb]] - rmFab + SIV gp160 + CD4 – rhesus monkey<br />
+
**[[7o9s]] - raFab + hantavirus envelope polyprotein <br />
 +
**[[7nks]], [[7nrh]] - raFab + hantavirus envelope polyprotein <br />
 +
**[[6z06]] - vFab + hantavirus envelope polyprotein – vole<br />
 +
**[[7b09]] - vFab + hantavirus envelope polyprotein - Cryo EM<br />
 +
**[[8tjs]], [[8top]] - maFab + gp120 + gp41 – Cryo EM <br />
 +
**[[7phv]], [[7phw]], [[7pi2]], [[7pi3]], [[7pi7]] - cFab + Cys-rich protective antigen – chicken<br />
 +
**[[8dzv]] - cFab anti troponin I + peptide<br />
 +
**[[8ezl]] – Fab + ookinete surface protein – Plasmodium falciparum<br />
*Fab: protein ternary complex
*Fab: protein ternary complex
**[[4cc8]] – hFab + gp41 + gp120<br />
**[[4cc8]] – hFab + gp41 + gp120<br />
 +
**[[8g4m]], [[8vgv]] – hFab + gp41 + gp120 – Cryo EM<br />
**[[3j70]] – hFab + gp41 + gp120 + CD4<br />
**[[3j70]] – hFab + gp41 + gp120 + CD4<br />
 +
**[[8ttw]] – hFab + gp41 + gp120 + drug – Cryo EM<br />
**[[4mxw]] – hFab anti-lymphotoxin-α + lymphotoxin-α + lymphotoxin-β + TNFR 3<br />
**[[4mxw]] – hFab anti-lymphotoxin-α + lymphotoxin-α + lymphotoxin-β + TNFR 3<br />
**[[6mid]] – hFab + zika E protein + zika M protein<br />
**[[6mid]] – hFab + zika E protein + zika M protein<br />
Line 387: Line 623:
**[[6nha]] – hFab + beta microglobulin + IgG receptor<br />
**[[6nha]] – hFab + beta microglobulin + IgG receptor<br />
**[[7kpb]] – hFab + TNF + TNFR<br />
**[[7kpb]] – hFab + TNF + TNFR<br />
-
**[[6b9z]] – hFab + protein L + immunoblobulin binding protein<br />
+
**[[4hkz]], [[6b9z]] – hFab + protein L + immunoblobulin binding protein<br />
**[[6b9y]], [[6bae]], [[6bah]] – hFab + protein L + meditope + immunoblobulin binding protein<br />
**[[6b9y]], [[6bae]], [[6bah]] – hFab + protein L + meditope + immunoblobulin binding protein<br />
 +
**[[8f60]] – rFab anti-BTLA + BTLA<br />
**[[3bsz]] – mFab + transthyretin + retinol-binding protein<br />
**[[3bsz]] – mFab + transthyretin + retinol-binding protein<br />
**[[2zck]] - mFab 8G8F5 + PSA + reaction intermediate<br />
**[[2zck]] - mFab 8G8F5 + PSA + reaction intermediate<br />
**[[3rhw]], [[3ri5]], [[3ria]], [[3rif]] – mFab + glutamate-gated Cl- channel + drug<br />
**[[3rhw]], [[3ri5]], [[3ria]], [[3rif]] – mFab + glutamate-gated Cl- channel + drug<br />
-
**[[2jk5]], [[2w0f]], [[2dwd]], [[2dwe]], [[2hvj]], [[2hvk]], [[2hg5]], [[1ors]], [[1zwi]] - mFab + KcsA K+ channel + ion<br />
+
**[[2jk5]], [[2w0f]], [[2dwd]], [[2dwe]], [[2hvj]], [[2hvk]], [[2hg5]], [[1ors]], [[1zwi]], [[7m2i]], [[7m2j]] - mFab + KcsA K+ channel + ion<br />
**[[3hpl]], [[2ih1]], [[2ih3]], [[1orq]] - mFab + KcsA K+ channel (mutant) + ion<br />
**[[3hpl]], [[2ih1]], [[2ih3]], [[1orq]] - mFab + KcsA K+ channel (mutant) + ion<br />
**[[1ynt]] – mFab 4F11E12 + protein L + major surface antigen p30<br />
**[[1ynt]] – mFab 4F11E12 + protein L + major surface antigen p30<br />
Line 398: Line 635:
**[[3klh]] – mFab + P66 RT + P51 RT + DNA<br />
**[[3klh]] – mFab + P66 RT + P51 RT + DNA<br />
**[[3w11]], [[3w12]] , [[3w13]] , [[4oga]], [[5kqv]] – mFab + insulin + insulin receptor<br />
**[[3w11]], [[3w12]] , [[3w13]] , [[4oga]], [[5kqv]] – mFab + insulin + insulin receptor<br />
 +
**[[5j3h]] – mFab + peptide + insulin receptor<br />
**[[1t03]] - mFab + Pol polyprotein + DNA<br />
**[[1t03]] - mFab + Pol polyprotein + DNA<br />
**[[1xcq]], [[1xct]], [[1xf5]] - mFab + capsid C + protein L<br />
**[[1xcq]], [[1xct]], [[1xf5]] - mFab + capsid C + protein L<br />
**[[1yyl]], [[1yym]] - mFab + gp120 + CD4 mimic<br />
**[[1yyl]], [[1yym]] - mFab + gp120 + CD4 mimic<br />
 +
**[[8dto]] - mFab + gp120 + gp41 – Cryo EM<br />
 +
**[[8d5c]] - mFab + gp160 + gp41 + CD4 – Cryo EM<br />
**[[2vdo]], [[2vdp]], [[2vdq]], [[2vdr]], [[4z7q]], [[4z7o]], [[4z7n]] - mFab + integrin + peptide<br />
**[[2vdo]], [[2vdp]], [[2vdq]], [[2vdr]], [[4z7q]], [[4z7o]], [[4z7n]] - mFab + integrin + peptide<br />
 +
**[[8tjr]] - maFab + gp160 + gp41 – Cryo EM<br />
**[[3ldb]] - CmFab + bifunctional arginine demethylase + α-ketogluterate<br />
**[[3ldb]] - CmFab + bifunctional arginine demethylase + α-ketogluterate<br />
Line 407: Line 648:
**[[1igy]] - hFab IgG1 <br />
**[[1igy]] - hFab IgG1 <br />
-
**[[1igt]], [[6rnn]], [[6rux]] – mFab <br />
+
**[[1igt]], [[1ynk]], [[1ynl]], [[6rnn]], [[6rux]] – mFab <br />
*Fc Fragments
*Fc Fragments
**[[1fcc]] - hFc IgG + streptococcal protein G C2 fragment<br />
**[[1fcc]] - hFc IgG + streptococcal protein G C2 fragment<br />
 +
**[[5iw3]], [[5iw6]]- hFc anti-CD20<br />
 +
**[[2rgs]] - mFc IgG2B <br />
 +
**[[8vev]] - mFc IgG anti M6A <br />
*Fv Fragments
*Fv Fragments
**[[1ap2]] – mFv C219 <br />
**[[1ap2]] – mFv C219 <br />
-
**[[1cfv]] – mFv FV4155 <br />
+
**[[1bfv]], [[1cfv]], [[2bfv]] – mFv FV4155 <br />
 +
**[[1a7n]], [[1a7o]], [[1a7p]], [[1a7q]], [[1a7r]] – mFv FVD1.3 <br />
 +
**[[8iqq]], [[8iqr]], [[8iqs]] – mFv M9 + PEG <br />
*Catalytic antibody
*Catalytic antibody
Line 456: Line 702:
* Single chain variable fragment (scFv)
* Single chain variable fragment (scFv)
-
**[[6ehy]], [[6ehx]], [[6ehw]], [[6ehv]], [[5j75]], [[5j74]], [[5c2b]], [[2a9n]], [[2a9m]], [[6tcs]] – hscFv<br />
+
**[[2a9m]], [[2a9n]], [[3juy]], [[4buh]], [[4ut7]], [[5c2b]], [[5c6w]], [[5j74]], [[5j75]], [[5wym]], [[6dn0]], [[6dsi]], [[6ehv]], [[6ehw]], [[6ehy]], [[6ehx]], [[6ffj]], [[6nou]], [[6qb9]], [[6qf9]], [[6qfc]], [[6tcs]], [[7ah1]] – hscFv<br />
-
**[[6j9o]] – hscFv anti-influenza<br />
+
**[[6tco]], [[6tcr]], [[7kbm]], [[7kbo]] – hscFv (mutant)<br />
-
**[[5wn9]], [[4kv5]] – hscFv + peptide<br />
+
**[[8ia6]] – hscFv anti-phopholipase<br />
-
**[[1n4x]], [[1moe]], [[5vf2]], [[5i4f]], [[5b3n]], [[4nko]], [[4nkm]], [[4nkd]], [[4h0i]], [[4h0g]], [[4gqp]], [[3umt]], [[3nn8]] – mscFv<br />
+
**[[4kv5]], [[8h3b]], [[8h73]] – hscFv + peptide<br />
-
**[[4p49]], [[4p48]], [[4ouo]] – cscFv<br />
+
**[[6qb4]] – hscFv + inhibitor<br />
-
**[[5yy4]], [[5yd5]], [[5yd4]], [[5yd3]], [[5fxc]], [[5a2l]], [[5a2j]], [[4h0h]] – mscFv + peptide<br />
+
**[[6uup]] – cascFv - camelidae<br />
 +
**[[8jza]] – cascFv anti-thyroglobulin<br />
 +
**[[6uy3]] – cascFv + MTX<br />
 +
**[[1n4x]], [[1moe]], [[3nn8]], [[3umt]], [[4gqp]], [[4h0g]], [[4h0i]], [[4nkd]], [[4nkm]], [[4nko]], [[5bn3n]], [[5i4f]], [[5vf2]], [[6p79]], [[6s2i]], [[6tnp]], [[6zqk]], [[7aql]], [[7url]] – mscFv<br />
 +
**[[8vrr]] – mscFv anti-CD34<br />
 +
**[[6k4z]] – mscFv + antigen<br />
 +
**[[4h0h]], [[5a2i]], [[5a2j]], [[5a2k]], [[5a2l]], [[5fxc]], [[5owp]], [[5yd3]], [[5yd4]], [[5yd5]], [[5yy4]], [[6frj]], [[6fzr]], [[6tgg]] – mscFv + peptide<br />
 +
**[[6fzq]] – mscFv + peptide + antigen<br />
 +
**[[6pil]], [[6pk8]], [[6psc]] – rscFv<br />
 +
**[[4ouo]], [[4p48]], [[4p49]] – cscFv<br />
 +
**[[6qf6]] – EcscFv<br />
-
*scFv: protein complex
+
*scFv protein complex
-
**[[6ck9]] – hscFv + hFab + Gp41<br />
 
-
**[[5uk2]], [[5uk1]], [[5uk0]], [[5ujz]], [[4yjz]] – hscFv + hemagglutinin<br />
 
**[[5m2j]] – hscFv + TNF<br />
**[[5m2j]] – hscFv + TNF<br />
**[[5jz7]] – hscFv + NGF<br />
**[[5jz7]] – hscFv + NGF<br />
**[[5jym]], [[5jyl]] – hscFv + cadherin<br />
**[[5jym]], [[5jyl]] – hscFv + cadherin<br />
-
**[[7jum]] – hscFv + Pfs230<br />
+
**[[3h3b]], [[6j71]] - hscFv + ERBB-2<br />
-
**[[6j71]] - hscFv + ERBB-2<br />
+
**[[7cu5]] - hscFv + PD-1<br />
 +
**[[7xw7]] – hscFv thyrotropin receptor – Cryo EM<br />
 +
**[[7vdh]], [[7vv5]] – hscFv in MRGPRX2 receptor – Cryo EM<br />
 +
**[[7vdl]], [[7vv3]] – hscFv in MRGPRX2 receptor + cortistatin – Cryo EM<br />
 +
**[[7vdm]] – hscFv in MRGPRX2 receptor + protachykinin – Cryo EM<br />
 +
**[[7vuy]], [[7vuz]] – hscFv in MRGPRX2 receptor + PAMP-12 – Cryo EM<br />
 +
**[[6ol6]], [[6ol7]] – hscFv + hFab <br />
 +
**[[6y6c]], [[6yye]] – hscFv + TREM-2 <br />
 +
**[[6qb3]] – hscFv + MCL-1 <br />
 +
**[[7vyt]] – hscFv + TIGIT <br />
 +
**[[6g8r]] – hscFv + SP140 <br />
 +
**[[8dy1]] – hscFv + IL-17A<br />
 +
**[[6kn9]] – hscFv + IL-1R<br />
 +
**[[8cz8]] – hscFv + mesothelin<br />
 +
**[[7df1]] – hscFv + CD98<br />
 +
**[[6i07]] - hscFv + EPCAM<br />
 +
**[[8rz0]], [[8rz1]]- hscFv + immunogen<br />
 +
**[[7vyt]] – hscFv + DIGIT<br />
 +
**[[8pwx]], [[8pww]] - hscFab + reticulocyte binding protein<br />
 +
**[[8gho]] - hscFab + guanylyl cyclase peptide<br />
 +
**[[8tw3]] – lgscFv + metapneumovirus glycoprotein <br />
**[[5f3j]] – mscFv + Duffy receptor<br />
**[[5f3j]] – mscFv + Duffy receptor<br />
**[[6eqc]], [[5ogi]] – mscFv + hexon protein<br />
**[[6eqc]], [[5ogi]] – mscFv + hexon protein<br />
**[[5lxa]] – mscFv + adiponectin receptor<br />
**[[5lxa]] – mscFv + adiponectin receptor<br />
-
**[[5kve]] – mscFv + Zika envelop protein<br />
 
-
**[[5kov]] – mscFv + vp90<br />
 
**[[3ab0]] – mscFv + BCLA protein<br />
**[[3ab0]] – mscFv + BCLA protein<br />
**[[2znx]], [[1dzb]] – mscFv + lysozyme<br />
**[[2znx]], [[1dzb]] – mscFv + lysozyme<br />
**[[2kh2]] – mscFv + interleukin<br />
**[[2kh2]] – mscFv + interleukin<br />
 +
**[[7zwf]], [[7zwm]] – mscFv + P45/48<br />
 +
**[[7jtr]] – mscFv + MBP<br />
 +
**[[4yqx]] – mscFv + IL-2<br />
 +
**[[7urv]] – mscFv + CD19<br />
 +
**[[8vrs]] – mscFv + MUCIN-16 peptide<br />
 +
**[[6sxi]] – mscFv + hFab <br />
 +
**[[6njl]], [[6njn]], [[7ldd]], [[7lde]] – mscFv in AMPA receptor – Cryo EM<br />
 +
**[[7xwo]] – mscFv in neurokinin receptor – Cryo EM<br />
 +
**[[6k41]], [[6k42]], [[7w6p]], [[7w7e]] – mscFv + adrenergic receptor + Gi + agonist – Cryo EM<br />
 +
**[[7w7e]] – hscFv + opsin + Gi – Cryo EM<br />
 +
**[[7tmw]] – lgVHH + relaxin receptor + Gi – Cryo EM<br />
 +
**[[6dzt]], [[6e0c]], [[6e0p]], [[7k61]], [[7k78]], [[7vbm]] – mscFv in nucleosome – Cryo EM<br />
 +
**[[8cxc]] – mscFv + hFab + mesothelin<br />
 +
**[[6dzw]], [[6dzy]] – mscFv + hFab + serotonin transporter – Cryo EM<br />
 +
**[[8xq3]] – mscFv + Nipah virus protein – Cryo EM<br />
 +
**[[7t6u]] – rascFv + hFab + formyl peptide receptor – Cryo EM<br />
 +
**[[8jd5]], [[8jd6]] – EcscFv + mGlu receptor + GI1 – Cryo EM<br />
 +
**[[8sps]], [[8spu]] – EcscFv in nucleosome – Cryo EM<br />
 +
 +
*scFv viral protein complex
 +
 +
**[[6ck9]] – hscFv + hFab + Gp41<br />
 +
**[[5wdu]], [[6mtj]], [[6mtn]], [[6mu6]], [[6mu7]], [[6mu8]], [[6muf]], [[6mug]], [[6nm6]] – hscFv + hFab + Gp160<br />
 +
**[[6vzi]], [[6w03]] – hscFv + hFab + Gp41 + Gp160<br />
 +
**[[5d9q]], [[6wix]] – hscFv + hFab + Gp41 + Gp120<br />
 +
**[[8d0y]] – mascFv + maFab + Gp41 + Gp120<br />
 +
**[[6nnf]], [[6nnj]] – hscFv + hFab + Gp41 + Gp120 + Gp160<br />
 +
**[[4yjz]], [[5uk2]], [[5uk1]], [[5uk0]], [[5ujz]] – hscFv + hemagglutinin<br />
 +
**[[7swd]] – hscFv + Ebola protein<br />
 +
**[[6pcu]] - hscFv + rotavirus VP4<br />
 +
**[[7qqb]] – hscFv + puumala virus protein<br />
 +
**[[[7pa6]], [7pa7]], [[7paa]], [[8u5l]] – hscFv + polyoma virus protein<br />
 +
**[[4ut9]], [[7a3o]], [[7a3p]], [[7a3q]], [[7a3t]] – hscFv + dengue protein<br />
 +
**[[7cth]] – hscFv + dengue protein – Cryo EM<br />
 +
**[[6tou]] – hscFv + rabies protein<br />
 +
**[[7bem]], [[7cyv]], [[7vmu]], [[8gpy]] – hscFv + SARS spike RBD<br />
 +
**[[7yue]] – hscFv + SARS spike peptide<br />
 +
**[[8cxg]] – hscFv + Zika envelop protein – Cryo EM<br />
 +
**[[7fei]], [[7fej]], [[8grr]], [[8gsp]] – scFv + foot-and-mouth virus proteins – bovine – Cryo EM<br />
 +
**[[5kve]] – mscFv + Zika envelop protein<br />
 +
**[[5kov]] – mscFv + astrovirus vp90<br />
 +
**[[6j11]] – mscFv + MERS spike N-terminal<br />
 +
**[[8dce]] – mscFv + SARS spike RBD<br />
 +
**[[7t3m]] – mscFv + SARS spike RBD – Cryo EM<br />
 +
**[[7k93]] – mscFv + dengue protein<br />
 +
**[[6h3t]], [[6h3u]] – mscFv + schmalenberg virus protein<br />
 +
**[[7rk1]], [[7rk2]] – mscFv + astrovirus protein<br />
 +
**[[6lgw]] – mscFv + rabies protein<br />
 +
**[[6cvk]], [[6cwd]] – rscFv + hepatitis B protein<br />
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D structures of Monoclonal Antibody

Updated on 06-November-2024

Humanized mouse antibody (hmFab) is a modified mFab which resembles more hFab.


Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Jaime Prilusky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Monoclonal_Antibodies_3D_structures"
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