1rxl

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==Solution structure of the engineered protein Afae-dsc==
==Solution structure of the engineered protein Afae-dsc==
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<StructureSection load='1rxl' size='340' side='right'caption='[[1rxl]], [[NMR_Ensembles_of_Models | 15 NMR models]]' scene=''>
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<StructureSection load='1rxl' size='340' side='right'caption='[[1rxl]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1rxl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RXL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RXL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1rxl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RXL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RXL FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1sdd|1sdd]], [[1ut2|1ut2]], [[1ut1|1ut1]], [[1usq|1usq]], [[1usz|1usz]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 15 models</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">afae3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rxl OCA], [https://pdbe.org/1rxl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rxl RCSB], [https://www.ebi.ac.uk/pdbsum/1rxl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rxl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rxl OCA], [https://pdbe.org/1rxl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rxl RCSB], [https://www.ebi.ac.uk/pdbsum/1rxl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rxl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/AFAE3_ECOLX AFAE3_ECOLX]] Hemagglutinins of uropathogenic E.coli mediate adherence to the upper urinary tract. These adhesins bind to the Dr blood group antigen and also agglutinate human erythrocytes in the presence of D-mannose (mannose-resistant hemagglutination (MRHA)).
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[https://www.uniprot.org/uniprot/AFAE3_ECOLX AFAE3_ECOLX] Hemagglutinins of uropathogenic E.coli mediate adherence to the upper urinary tract. These adhesins bind to the Dr blood group antigen and also agglutinate human erythrocytes in the presence of D-mannose (mannose-resistant hemagglutination (MRHA)).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rx/1rxl_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rx/1rxl_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Anderson, K L]]
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[[Category: Anderson KL]]
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[[Category: Barlow, P N]]
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[[Category: Barlow PN]]
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[[Category: Billington, J]]
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[[Category: Billington J]]
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[[Category: Bouguenec, C Le]]
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[[Category: Chen HA]]
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[[Category: Chen, H A]]
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[[Category: Cota E]]
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[[Category: Cota, E]]
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[[Category: Le Bouguenec C]]
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[[Category: Lea, S M]]
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[[Category: Lea SM]]
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[[Category: Matthews, S]]
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[[Category: Matthews S]]
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[[Category: Medof, M E]]
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[[Category: Medof ME]]
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[[Category: Merle, L du]]
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[[Category: Nowicki B]]
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[[Category: Nowicki, B]]
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[[Category: Pettigrew D]]
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[[Category: Pettigrew, D]]
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[[Category: Roversi P]]
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[[Category: Roversi, P]]
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[[Category: Simpson P]]
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[[Category: Simpson, P]]
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[[Category: Smith RA]]
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[[Category: Smith, R A]]
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[[Category: Urvil P]]
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[[Category: Urvil, P]]
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[[Category: Du Merle L]]
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[[Category: Afae]]
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[[Category: Afimbrial sheath]]
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[[Category: Daec]]
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[[Category: Daf]]
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[[Category: Donor strand complemented]]
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[[Category: Ig-like domain]]
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[[Category: Structural protein]]
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[[Category: Upec]]
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Current revision

Solution structure of the engineered protein Afae-dsc

PDB ID 1rxl

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