2jwt

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==Solution structure of Engrailed homeodomain WT==
==Solution structure of Engrailed homeodomain WT==
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<StructureSection load='2jwt' size='340' side='right'caption='[[2jwt]], [[NMR_Ensembles_of_Models | 25 NMR models]]' scene=''>
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<StructureSection load='2jwt' size='340' side='right'caption='[[2jwt]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2jwt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JWT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JWT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2jwt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JWT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JWT FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1enh|1enh]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">en ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jwt OCA], [https://pdbe.org/2jwt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jwt RCSB], [https://www.ebi.ac.uk/pdbsum/2jwt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jwt ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jwt OCA], [https://pdbe.org/2jwt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jwt RCSB], [https://www.ebi.ac.uk/pdbsum/2jwt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jwt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/HMEN_DROME HMEN_DROME]] This protein specifies the body segmentation pattern. It is required for the development of the central nervous system. Transcriptional regulator that represses activated promoters. Wg signaling operates by inactivating the SGG repression of EN autoactivation.
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[https://www.uniprot.org/uniprot/HMEN_DROME HMEN_DROME] This protein specifies the body segmentation pattern. It is required for the development of the central nervous system. Transcriptional regulator that represses activated promoters. Wg signaling operates by inactivating the SGG repression of EN autoactivation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Drome]]
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[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Religa, T L]]
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[[Category: Religa TL]]
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[[Category: Developmental protein]]
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[[Category: Dna-binding]]
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[[Category: Homeobox]]
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[[Category: Homeodomain]]
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[[Category: Nucleus]]
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[[Category: Phosphorylation]]
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[[Category: Repressor]]
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[[Category: Segmentation polarity protein]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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Current revision

Solution structure of Engrailed homeodomain WT

PDB ID 2jwt

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