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7syk
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7syk is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 5(delta dII)== | |
| - | + | <StructureSection load='7syk' size='340' side='right'caption='[[7syk]], [[Resolution|resolution]] 4.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7syk]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SYK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SYK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7syk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7syk OCA], [https://pdbe.org/7syk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7syk RCSB], [https://www.ebi.ac.uk/pdbsum/7syk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7syk ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/G1TLT8_RABIT G1TLT8_RABIT] Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.[HAMAP-Rule:MF_03016] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Oryctolagus cuniculus]] | ||
| + | [[Category: Abaeva IS]] | ||
| + | [[Category: Brown ZP]] | ||
| + | [[Category: De S]] | ||
| + | [[Category: Frank J]] | ||
| + | [[Category: Hellen CUT]] | ||
| + | [[Category: Pestova TV]] | ||
Current revision
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 5(delta dII)
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