6zg4
From Proteopedia
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<StructureSection load='6zg4' size='340' side='right'caption='[[6zg4]], [[Resolution|resolution]] 2.33Å' scene=''> | <StructureSection load='6zg4' size='340' side='right'caption='[[6zg4]], [[Resolution|resolution]] 2.33Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'> | + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZG4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZG4 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=QK8:ethyl+(4~{S})-4-[4-[(1-methylcyclobutyl)carbamoyl]piperidin-1-yl]azepane-1-carboxylate'>QK8</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.33Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=QK8:ethyl+(4~{S})-4-[4-[(1-methylcyclobutyl)carbamoyl]piperidin-1-yl]azepane-1-carboxylate'>QK8</scene></td></tr> | |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zg4 OCA], [https://pdbe.org/6zg4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zg4 RCSB], [https://www.ebi.ac.uk/pdbsum/6zg4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zg4 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zg4 OCA], [https://pdbe.org/6zg4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zg4 RCSB], [https://www.ebi.ac.uk/pdbsum/6zg4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zg4 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [[https://www.uniprot.org/uniprot/ACM1_HUMAN ACM1_HUMAN]] The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. | ||
==See Also== | ==See Also== | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Cooke RM]] | |
| - | [[Category: Cooke | + | [[Category: Rucktooa P]] |
| - | [[Category: Rucktooa | + | |
| - | + | ||
| - | + | ||
Current revision
Structure of M1-StaR-T4L in complex with HTL0009936 at 2.35A
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