2d3j
From Proteopedia
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==NMR structure of the WIF domain from human WIF-1== | ==NMR structure of the WIF domain from human WIF-1== | ||
| - | <StructureSection load='2d3j' size='340' side='right'caption='[[2d3j | + | <StructureSection load='2d3j' size='340' side='right'caption='[[2d3j]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2d3j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2d3j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D3J FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d3j OCA], [https://pdbe.org/2d3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d3j RCSB], [https://www.ebi.ac.uk/pdbsum/2d3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d3j ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d3j OCA], [https://pdbe.org/2d3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d3j RCSB], [https://www.ebi.ac.uk/pdbsum/2d3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d3j ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/WIF1_HUMAN WIF1_HUMAN] Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d3/2d3j_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d3/2d3j_consurf.spt"</scriptWhenChecked> | ||
| - | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Banyai | + | [[Category: Banyai L]] |
| - | [[Category: Liepinsh | + | [[Category: Liepinsh E]] |
| - | [[Category: Otting | + | [[Category: Otting G]] |
| - | [[Category: Patthy | + | [[Category: Patthy L]] |
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Current revision
NMR structure of the WIF domain from human WIF-1
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