7ery

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:11, 3 April 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='7ery' size='340' side='right'caption='[[7ery]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
<StructureSection load='7ery' size='340' side='right'caption='[[7ery]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[7ery]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ERY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ERY FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[7ery]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa_Japonica_Group Oryza sativa Japonica Group]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ERY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ERY FirstGlance]. <br>
-
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7erx|7erx]]</div></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ery FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ery OCA], [https://pdbe.org/7ery PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ery RCSB], [https://www.ebi.ac.uk/pdbsum/7ery PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ery ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ery FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ery OCA], [https://pdbe.org/7ery PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ery RCSB], [https://www.ebi.ac.uk/pdbsum/7ery PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ery ProSAT]</span></td></tr>
</table>
</table>
-
<div style="background-color:#fffaf0;">
+
== Function ==
-
== Publication Abstract from PubMed ==
+
[https://www.uniprot.org/uniprot/Q0DPB7_ORYSJ Q0DPB7_ORYSJ]
-
Steviol glycosides are the intensely sweet components of extracts from Stevia rebaudiana. These molecules comprise an invariant steviol aglycone decorated with variable glycans and could widely serve as a low-calorie sweetener. However, the most desirable steviol glycosides Reb D and Reb M, devoid of unpleasant aftertaste, are naturally produced only in trace amounts due to low levels of specific beta (1-2) glucosylation in Stevia. Here, we report the biochemical and structural characterization of OsUGT91C1, a glycosyltransferase from Oryza sativa, which is efficient at catalyzing beta (1-2) glucosylation. The enzyme's ability to bind steviol glycoside substrate in three modes underlies its flexibility to catalyze beta (1-2) glucosylation in two distinct orientations as well as beta (1-6) glucosylation. Guided by the structural insights, we engineer this enzyme to enhance the desirable beta (1-2) glucosylation, eliminate beta (1-6) glucosylation, and obtain a promising catalyst for the industrial production of naturally rare but palatable steviol glycosides.
+
-
Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides.,Zhang J, Tang M, Chen Y, Ke D, Zhou J, Xu X, Yang W, He J, Dong H, Wei Y, Naismith JH, Lin Y, Zhu X, Cheng W Nat Commun. 2021 Dec 2;12(1):7030. doi: 10.1038/s41467-021-27144-4. PMID:34857750<ref>PMID:34857750</ref>
+
==See Also==
-
 
+
*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
-
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+
-
</div>
+
-
<div class="pdbe-citations 7ery" style="background-color:#fffaf0;"></div>
+
-
== References ==
+
-
<references/>
+
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Zhu, X]]
+
[[Category: Oryza sativa Japonica Group]]
-
[[Category: Glycosyltransferase apo form]]
+
[[Category: Zhu X]]
-
[[Category: Transferase]]
+

Current revision

apo form of the glycosyltransferase

PDB ID 7ery

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/7ery"
Personal tools