2ee4

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Current revision (18:50, 29 May 2024) (edit) (undo)
 
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==Solution structure of the RhoGAP domain from human Rho GTPase activating protein 5 variant==
==Solution structure of the RhoGAP domain from human Rho GTPase activating protein 5 variant==
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<StructureSection load='2ee4' size='340' side='right'caption='[[2ee4]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2ee4' size='340' side='right'caption='[[2ee4]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ee4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EE4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EE4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ee4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EE4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EE4 FirstGlance]. <br>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Small_monomeric_GTPase Small monomeric GTPase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.5.2 3.6.5.2] </span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ee4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ee4 OCA], [https://pdbe.org/2ee4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ee4 RCSB], [https://www.ebi.ac.uk/pdbsum/2ee4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ee4 ProSAT], [https://www.topsan.org/Proteins/RSGI/2ee4 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ee4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ee4 OCA], [https://pdbe.org/2ee4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ee4 RCSB], [https://www.ebi.ac.uk/pdbsum/2ee4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ee4 ProSAT], [https://www.topsan.org/Proteins/RSGI/2ee4 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/RHG05_HUMAN RHG05_HUMAN]] GTPase-activating protein for Rho family members. May play a role in the reduction of the p21rasGTPase-activating potential of RASA1/p120GAP.
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[https://www.uniprot.org/uniprot/RHG05_HUMAN RHG05_HUMAN] GTPase-activating protein for Rho family members. May play a role in the reduction of the p21rasGTPase-activating potential of RASA1/p120GAP.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Small monomeric GTPase]]
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[[Category: Harada T]]
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[[Category: Harada, T]]
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[[Category: Kigawa T]]
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[[Category: Kigawa, T]]
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[[Category: Koshiba S]]
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[[Category: Koshiba, S]]
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[[Category: Tochio N]]
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[[Category: Structural genomic]]
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[[Category: Tomizawa T]]
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[[Category: Tochio, N]]
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[[Category: Watanabe S]]
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[[Category: Tomizawa, T]]
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[[Category: Yokoyama S]]
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[[Category: Watanabe, S]]
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[[Category: Yokoyama, S]]
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[[Category: All alpha protein]]
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[[Category: Gtpase-activating protein for rho family member]]
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[[Category: Hydrolase]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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Current revision

Solution structure of the RhoGAP domain from human Rho GTPase activating protein 5 variant

PDB ID 2ee4

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