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7vie

From Proteopedia

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Current revision (06:18, 28 September 2022) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 7vie is ON HOLD until Paper Publication
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==Cryo-EM structure of Gi coupled Sphingosine 1-phosphate receptor bound with S1P==
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<StructureSection load='7vie' size='340' side='right'caption='[[7vie]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7vie]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VIE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VIE FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=S1P:(2S,3R,4E)-2-AMINO-3-HYDROXYOCTADEC-4-EN-1-YL+DIHYDROGEN+PHOSPHATE'>S1P</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vie OCA], [https://pdbe.org/7vie PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vie RCSB], [https://www.ebi.ac.uk/pdbsum/7vie PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vie ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN]] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Gan B]]
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[[Category: Ren RB]]
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[[Category: Xiao QJ]]
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[[Category: Yu LY]]

Current revision

Cryo-EM structure of Gi coupled Sphingosine 1-phosphate receptor bound with S1P

PDB ID 7vie

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OCA

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