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7vqn
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of KPC-2 beta-lactamase complexed with hydrolyzed EXW-1== | |
| + | <StructureSection load='7vqn' size='340' side='right'caption='[[7vqn]], [[Resolution|resolution]] 2.34Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7vqn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VQN FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.34Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7TC:(2R,3S)-3-methyl-4-methylidene-2-[(2S,3R)-3-oxidanyl-1-oxidanylidene-butan-2-yl]-2,3-dihydropyrrole-5-carboxylic+acid'>7TC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vqn OCA], [https://pdbe.org/7vqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vqn RCSB], [https://www.ebi.ac.uk/pdbsum/7vqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vqn ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BLKPC_KLEPN BLKPC_KLEPN] Hydrolyzes carbapenems, penicillins, cephalosporins and monobactams with varying efficiency. | ||
| - | + | ==See Also== | |
| - | + | *[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Xie | + | [[Category: Klebsiella pneumoniae]] |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Xie HX]] | ||
Current revision
Crystal structure of KPC-2 beta-lactamase complexed with hydrolyzed EXW-1
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