This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7dp4
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of wild type Brugia malayi thymidylate synthase complexed with 2'-deoxyuridine monophosphate and methotrexate== | ==Crystal structure of wild type Brugia malayi thymidylate synthase complexed with 2'-deoxyuridine monophosphate and methotrexate== | ||
| - | <StructureSection load='7dp4' size='340' side='right'caption='[[7dp4]]' scene=''> | + | <StructureSection load='7dp4' size='340' side='right'caption='[[7dp4]], [[Resolution|resolution]] 1.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DP4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DP4 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7dp4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Brugia_malayi Brugia malayi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DP4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DP4 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dp4 OCA], [https://pdbe.org/7dp4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dp4 RCSB], [https://www.ebi.ac.uk/pdbsum/7dp4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dp4 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=MTX:METHOTREXATE'>MTX</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dp4 OCA], [https://pdbe.org/7dp4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dp4 RCSB], [https://www.ebi.ac.uk/pdbsum/7dp4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dp4 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A4E9EZW9_BRUMA A0A4E9EZW9_BRUMA] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Brugia malayi]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Canyuk B]] | [[Category: Canyuk B]] | ||
Current revision
Crystal structure of wild type Brugia malayi thymidylate synthase complexed with 2'-deoxyuridine monophosphate and methotrexate
| |||||||||||
