7dp4
From Proteopedia
(Difference between revisions)
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==Crystal structure of wild type Brugia malayi thymidylate synthase complexed with 2'-deoxyuridine monophosphate and methotrexate== | ==Crystal structure of wild type Brugia malayi thymidylate synthase complexed with 2'-deoxyuridine monophosphate and methotrexate== | ||
| - | <StructureSection load='7dp4' size='340' side='right'caption='[[7dp4]]' scene=''> | + | <StructureSection load='7dp4' size='340' side='right'caption='[[7dp4]], [[Resolution|resolution]] 1.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DP4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DP4 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7dp4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Brugia_malayi Brugia malayi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DP4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DP4 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dp4 OCA], [https://pdbe.org/7dp4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dp4 RCSB], [https://www.ebi.ac.uk/pdbsum/7dp4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dp4 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=MTX:METHOTREXATE'>MTX</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dp4 OCA], [https://pdbe.org/7dp4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dp4 RCSB], [https://www.ebi.ac.uk/pdbsum/7dp4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dp4 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A4E9EZW9_BRUMA A0A4E9EZW9_BRUMA] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Brugia malayi]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Canyuk B]] | [[Category: Canyuk B]] | ||
Current revision
Crystal structure of wild type Brugia malayi thymidylate synthase complexed with 2'-deoxyuridine monophosphate and methotrexate
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