This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2zza
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='2zza' size='340' side='right'caption='[[2zza]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='2zza' size='340' side='right'caption='[[2zza]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2zza]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2zza]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Moritella_profunda Moritella profunda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZZA FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> |
| - | < | + | |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zza OCA], [https://pdbe.org/2zza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zza RCSB], [https://www.ebi.ac.uk/pdbsum/2zza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zza ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zza OCA], [https://pdbe.org/2zza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zza RCSB], [https://www.ebi.ac.uk/pdbsum/2zza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zza ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/Q70YQ6_MORPR Q70YQ6_MORPR] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194] | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 26: | Line 25: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Dihydrofolate reductase]] | ||
| - | [[Category: Jcm 11435]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Akasaka, K]] | ||
| - | [[Category: Gekko, K]] | ||
| - | [[Category: Hata, K]] | ||
| - | [[Category: Murakami, C]] | ||
| - | [[Category: Ohmae, E]] | ||
| - | [[Category: Shiro, Y]] | ||
| - | [[Category: Tanaka, T]] | ||
| - | [[Category: Deep-sea]] | ||
| - | [[Category: Folic acid]] | ||
| - | [[Category: High pressure]] | ||
| - | [[Category: Low temperature]] | ||
[[Category: Moritella profunda]] | [[Category: Moritella profunda]] | ||
| - | [[Category: | + | [[Category: Akasaka K]] |
| - | [[Category: | + | [[Category: Gekko K]] |
| - | [[Category: | + | [[Category: Hata K]] |
| - | [[Category: | + | [[Category: Murakami C]] |
| - | [[Category: | + | [[Category: Ohmae E]] |
| + | [[Category: Shiro Y]] | ||
| + | [[Category: Tanaka T]] | ||
Current revision
Moritella profunda Dihydrofolate reductase complex with NADP+ and Folate
| |||||||||||
Categories: Large Structures | Moritella profunda | Akasaka K | Gekko K | Hata K | Murakami C | Ohmae E | Shiro Y | Tanaka T
