7fep

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'''Unreleased structure'''
 
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The entry 7fep is ON HOLD until Paper Publication
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==Cryo-EM structure of BsClpP-ADEP1 complex at pH 6.5==
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<StructureSection load='7fep' size='340' side='right'caption='[[7fep]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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Authors: Kim, L., Lee, B.-G., Kim, M.K., Kwon, D.H., Kim, H., Brotz-Oesterhelt, H., Roh, S.-H., Song, H.K.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7fep]] is a 28 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FEP FirstGlance]. <br>
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Description: Cryo-EM structure of BsClpP-ADEP1 complex at pH 6.5
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MAA:N-METHYL-L-ALANINE'>MAA</scene>, <scene name='pdbligand=MP8:(4R)-4-METHYL-L-PROLINE'>MP8</scene>, <scene name='pdbligand=OTT:(2E,4E,6E)-OCTA-2,4,6-TRIENOIC+ACID'>OTT</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fep OCA], [https://pdbe.org/7fep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fep RCSB], [https://www.ebi.ac.uk/pdbsum/7fep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fep ProSAT]</span></td></tr>
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[[Category: Kim, M.K]]
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</table>
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[[Category: Kim, H]]
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== Function ==
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[[Category: Brotz-Oesterhelt, H]]
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[[https://www.uniprot.org/uniprot/CLPP_BACSU CLPP_BACSU]] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity). ClpXP is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor.<ref>PMID:16899079</ref>
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[[Category: Kwon, D.H]]
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== References ==
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[[Category: Roh, S.-H]]
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<references/>
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[[Category: Lee, B.-G]]
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__TOC__
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[[Category: Kim, L]]
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</StructureSection>
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[[Category: Song, H.K]]
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[[Category: Bacillus subtilis]]
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[[Category: Large Structures]]
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[[Category: Synthetic construct]]
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[[Category: Brotz-Oesterhelt H]]
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[[Category: Kim H]]
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[[Category: Kim L]]
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[[Category: Kim MK]]
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[[Category: Kwon DH]]
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[[Category: Lee B-G]]
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[[Category: Roh S-H]]
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[[Category: Song HK]]

Current revision

Cryo-EM structure of BsClpP-ADEP1 complex at pH 6.5

PDB ID 7fep

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