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7taw
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7taw is ON HOLD Authors: Mukherjee, I.A., Chang, L. Description: Csy-AcrIF complex Category: Unreleased Structures Category: Chang, L [[Cat...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the Csy-AcrIF24-promoter DNA dimer== | |
| - | + | <StructureSection load='7taw' size='340' side='right'caption='[[7taw]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7taw]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas Pseudomonas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TAW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TAW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7taw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7taw OCA], [https://pdbe.org/7taw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7taw RCSB], [https://www.ebi.ac.uk/pdbsum/7taw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7taw ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: Chang | + | == Function == |
| - | [[Category: Mukherjee | + | [https://www.uniprot.org/uniprot/CSY1_PSEAB CSY1_PSEAB] CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Cas3 and Cascade participate in CRISPR interference, the third stage of CRISPR immunity (Potential). Involved in crRNA production or stability. The Csy ribonucleoprotein complex binds target ssDNA with high affinity but target dsDNA with much lower affinity.<ref>PMID:21398535</ref> <ref>PMID:22522703</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pseudomonas]] | ||
| + | [[Category: Chang L]] | ||
| + | [[Category: Mukherjee IA]] | ||
Current revision
Cryo-EM structure of the Csy-AcrIF24-promoter DNA dimer
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