7vbg

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Current revision (16:38, 7 September 2022) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 7vbg is ON HOLD until Paper Publication
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==N Terminal Domain of PRC1==
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<StructureSection load='7vbg' size='340' side='right'caption='[[7vbg]]' scene=''>
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Authors: Tan, F., Xia, B.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7vbg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VBG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VBG FirstGlance]. <br>
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Description: N Terminal Domain of PRC1
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vbg OCA], [https://pdbe.org/7vbg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vbg RCSB], [https://www.ebi.ac.uk/pdbsum/7vbg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vbg ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Xia, B]]
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== Function ==
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[[Category: Tan, F]]
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[[https://www.uniprot.org/uniprot/PRC1_HUMAN PRC1_HUMAN]] Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle.<ref>PMID:9885575</ref> <ref>PMID:12082078</ref> <ref>PMID:15297875</ref> <ref>PMID:15625105</ref> <ref>PMID:16431929</ref> <ref>PMID:19468300</ref> <ref>PMID:20691902</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Tan F]]
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[[Category: Xia B]]

Current revision

N Terminal Domain of PRC1

PDB ID 7vbg

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