This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1o6h

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:57, 9 May 2024) (edit) (undo)
 
(One intermediate revision not shown.)
Line 3: Line 3:
<StructureSection load='1o6h' size='340' side='right'caption='[[1o6h]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='1o6h' size='340' side='right'caption='[[1o6h]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1o6h]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_27009 Atcc 27009]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O6H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O6H FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1o6h]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Alicyclobacillus_acidocaldarius Alicyclobacillus acidocaldarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O6H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O6H FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene>, <scene name='pdbligand=W37:N-(6-{[1-(4-BROMOPHENYL)ISOQUINOLIN-6-YL]OXY}HEXYL)-N-METHYLPROP-2-EN-1-AMINE'>W37</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1gsz|1gsz]], [[1h35|1h35]], [[1h36|1h36]], [[1h37|1h37]], [[1h39|1h39]], [[1h3a|1h3a]], [[1h3b|1h3b]], [[1h3c|1h3c]], [[1o6q|1o6q]], [[1o6r|1o6r]], [[1o79|1o79]], [[1ump|1ump]], [[1sqc|1sqc]], [[2sqc|2sqc]], [[3sqc|3sqc]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene>, <scene name='pdbligand=W37:N-(6-{[1-(4-BROMOPHENYL)ISOQUINOLIN-6-YL]OXY}HEXYL)-N-METHYLPROP-2-EN-1-AMINE'>W37</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Squalene--hopene_cyclase Squalene--hopene cyclase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.17 5.4.99.17] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o6h OCA], [https://pdbe.org/1o6h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1o6h RCSB], [https://www.ebi.ac.uk/pdbsum/1o6h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o6h ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o6h OCA], [https://pdbe.org/1o6h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1o6h RCSB], [https://www.ebi.ac.uk/pdbsum/1o6h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o6h ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/SQHC_ALIAD SQHC_ALIAD] Catalyzes the cyclization of squalene into hopene.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 35: Line 36:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Atcc 27009]]
+
[[Category: Alicyclobacillus acidocaldarius]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Squalene--hopene cyclase]]
+
[[Category: Aebi JD]]
-
[[Category: Aebi, J D]]
+
[[Category: Dehmlow H]]
-
[[Category: Dehmlow, H]]
+
[[Category: Lenhart A]]
-
[[Category: Lenhart, A]]
+
[[Category: Morand OH]]
-
[[Category: Morand, O H]]
+
[[Category: Reinert DJ]]
-
[[Category: Reinert, D J]]
+
[[Category: Schulz GE]]
-
[[Category: Schulz, G E]]
+
[[Category: Weihofen WA]]
-
[[Category: Weihofen, W A]]
+
-
[[Category: Cholesterol biosynthesis]]
+
-
[[Category: Inhibitor]]
+
-
[[Category: Isomerase]]
+
-
[[Category: Monotopic membrane protein]]
+
-
[[Category: Oxidosqualene cyclase]]
+

Current revision

Squalene-Hopene Cyclase

PDB ID 1o6h

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1o6h"
Personal tools