1g1x

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[[Image:1g1x.gif|left|200px]]
 
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==STRUCTURE OF RIBOSOMAL PROTEINS S15, S6, S18, AND 16S RIBOSOMAL RNA==
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The line below this paragraph, containing "STRUCTURE_1g1x", creates the "Structure Box" on the page.
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<StructureSection load='1g1x' size='340' side='right'caption='[[1g1x]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1g1x]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ekc 1ekc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G1X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G1X FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g1x OCA], [https://pdbe.org/1g1x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g1x RCSB], [https://www.ebi.ac.uk/pdbsum/1g1x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g1x ProSAT]</span></td></tr>
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{{STRUCTURE_1g1x| PDB=1g1x | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RS6_THET8 RS6_THET8] Located on the outer edge of the platform on the body of the 30S subunit.[HAMAP-Rule:MF_00360]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g1/1g1x_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g1x ConSurf].
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<div style="clear:both"></div>
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'''STRUCTURE OF RIBOSOMAL PROTEINS S15, S6, S18, AND 16S RIBOSOMAL RNA'''
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==See Also==
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*[[Ribosomal protein S15|Ribosomal protein S15]]
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*[[Ribosomal protein S18|Ribosomal protein S18]]
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==Overview==
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*[[Ribosomal protein S6|Ribosomal protein S6]]
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The crystal structure of a 70-kilodalton ribonucleoprotein complex from the central domain of the Thermus thermophilus 30S ribosomal subunit was solved at 2.6 angstrom resolution. The complex consists of a 104-nucleotide RNA fragment composed of two three-helix junctions that lie at the end of a central helix, and the ribosomal proteins S15, S6, and S18. S15 binds the ribosomal RNA early in the assembly of the 30S ribosomal subunit, stabilizing a conformational reorganization of the two three-helix junctions that creates the RNA fold necessary for subsequent binding of S6 and S18. The structure of the complex demonstrates the central role of S15-induced reorganization of central domain RNA for the subsequent steps of ribosome assembly.
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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1G1X is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ekc 1ekc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G1X OCA].
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==Reference==
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Structure of the S15,S6,S18-rRNA complex: assembly of the 30S ribosome central domain., Agalarov SC, Sridhar Prasad G, Funke PM, Stout CD, Williamson JR, Science. 2000 Apr 7;288(5463):107-13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10753109 10753109]
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[[Category: Protein complex]]
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[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Agalarov, S C.]]
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[[Category: Agalarov SC]]
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[[Category: Funke, P M.]]
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[[Category: Funke PM]]
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[[Category: Prasad, G S.]]
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[[Category: Prasad GS]]
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[[Category: Stout, C D.]]
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[[Category: Stout CD]]
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[[Category: Williamson, J R.]]
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[[Category: Williamson JR]]
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[[Category: Ribosomal proteins s15]]
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[[Category: Ribosome]]
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[[Category: Rna]]
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[[Category: S18]]
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[[Category: S30 ribosomal subunit]]
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[[Category: S6]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 17:01:54 2008''
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Current revision

STRUCTURE OF RIBOSOMAL PROTEINS S15, S6, S18, AND 16S RIBOSOMAL RNA

PDB ID 1g1x

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