7w49
From Proteopedia
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| - | ==== | + | ==Crystal structure of the gastric proton pump complexed with soraprazan== |
| - | <StructureSection load='7w49' size='340' side='right'caption='[[7w49]]' scene=''> | + | <StructureSection load='7w49' size='340' side='right'caption='[[7w49]], [[Resolution|resolution]] 3.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7w49]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7W49 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7W49 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7w49 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7w49 OCA], [https://pdbe.org/7w49 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7w49 RCSB], [https://www.ebi.ac.uk/pdbsum/7w49 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7w49 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8CE:Soraprazan'>8CE</scene>, <scene name='pdbligand=BFD:ASPARTATE+BERYLLIUM+TRIFLUORIDE'>BFD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=RB:RUBIDIUM+ION'>RB</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7w49 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7w49 OCA], [https://pdbe.org/7w49 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7w49 RCSB], [https://www.ebi.ac.uk/pdbsum/7w49 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7w49 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ATP4A_PIG ATP4A_PIG] Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[ATPase 3D structures|ATPase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Sus scrofa]] |
| + | [[Category: Abe K]] | ||
| + | [[Category: Tanaka S]] | ||
Current revision
Crystal structure of the gastric proton pump complexed with soraprazan
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