3bhd

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:48, 30 October 2024) (edit) (undo)
 
(One intermediate revision not shown.)
Line 3: Line 3:
<StructureSection load='3bhd' size='340' side='right'caption='[[3bhd]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='3bhd' size='340' side='right'caption='[[3bhd]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3bhd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BHD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BHD FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3bhd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BHD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BHD FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">THTPA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Thiamine-triphosphatase Thiamine-triphosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.28 3.6.1.28] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bhd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bhd OCA], [https://pdbe.org/3bhd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bhd RCSB], [https://www.ebi.ac.uk/pdbsum/3bhd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bhd ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bhd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bhd OCA], [https://pdbe.org/3bhd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bhd RCSB], [https://www.ebi.ac.uk/pdbsum/3bhd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bhd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/THTPA_HUMAN THTPA_HUMAN]] Hydrolase highly specific for thiamine triphosphate (ThTP).
+
[https://www.uniprot.org/uniprot/THTPA_HUMAN THTPA_HUMAN] Hydrolase highly specific for thiamine triphosphate (ThTP).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 17: Line 15:
<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bh/3bhd_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bh/3bhd_consurf.spt"</scriptWhenChecked>
-
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
Line 24: Line 22:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Thiamine-triphosphatase]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Arrowsmith, C H]]
+
[[Category: Berglund H]]
-
[[Category: Berg, S Van den]]
+
[[Category: Busam RD]]
-
[[Category: Berglund, H]]
+
[[Category: Collins R]]
-
[[Category: Busam, R D]]
+
[[Category: Dahlgren LG]]
-
[[Category: Collins, R]]
+
[[Category: Edwards AM]]
-
[[Category: Dahlgren, L G]]
+
[[Category: Flodin S]]
-
[[Category: Edwards, A M]]
+
[[Category: Flores A]]
-
[[Category: Flodin, S]]
+
[[Category: Graslund S]]
-
[[Category: Flores, A]]
+
[[Category: Hallberg BM]]
-
[[Category: Graslund, S]]
+
[[Category: Hammarstrom M]]
-
[[Category: Hallberg, B M]]
+
[[Category: Herman MD]]
-
[[Category: Hammarstrom, M]]
+
[[Category: Johansson A]]
-
[[Category: Herman, M D]]
+
[[Category: Johansson I]]
-
[[Category: Johansson, A]]
+
[[Category: Kallas A]]
-
[[Category: Johansson, I]]
+
[[Category: Karlberg T]]
-
[[Category: Kallas, A]]
+
[[Category: Kotenyova T]]
-
[[Category: Karlberg, T]]
+
[[Category: Lehtio L]]
-
[[Category: Kotenyova, T]]
+
[[Category: Moche M]]
-
[[Category: Lehtio, L]]
+
[[Category: Nilsson ME]]
-
[[Category: Moche, M]]
+
[[Category: Nordlund P]]
-
[[Category: Nilsson, M E]]
+
[[Category: Nyman T]]
-
[[Category: Nordlund, P]]
+
[[Category: Persson C]]
-
[[Category: Nyman, T]]
+
[[Category: Sagemark J]]
-
[[Category: Persson, C]]
+
[[Category: Sundstrom M]]
-
[[Category: Structural genomic]]
+
[[Category: Svensson L]]
-
[[Category: Sagemark, J]]
+
[[Category: Thorsell AG]]
-
[[Category: Sundstrom, M]]
+
[[Category: Tresaugues L]]
-
[[Category: Svensson, L]]
+
[[Category: Van den Berg S]]
-
[[Category: Thorsell, A G]]
+
[[Category: Weigelt J]]
-
[[Category: Tresaugues, L]]
+
[[Category: Welin M]]
-
[[Category: Weigelt, J]]
+
-
[[Category: Welin, M]]
+
-
[[Category: Cyth domain]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Phosphatase]]
+
-
[[Category: Sgc]]
+

Current revision

Crystal structure of human thiamine triphosphatase (THTPA)

PDB ID 3bhd

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3bhd"
Personal tools