7thi

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "7thi" [edit=sysop:move=sysop])
Current revision (17:04, 18 October 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 7thi is ON HOLD
+
==Human Bisphosphoglycerate Mutase complexed with 2-phosphoglycolate==
-
 
+
<StructureSection load='7thi' size='340' side='right'caption='[[7thi]], [[Resolution|resolution]] 1.33&Aring;' scene=''>
-
Authors: Clark, K.L., Kulathila, R., Wright, K., Isome, Y., Sage, D., Yang, Y., Christodoulou, C.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[7thi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7THI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7THI FirstGlance]. <br>
-
Description: Human Bisphosphoglycerate Mutase complexed with 2-phosphoglycolate
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.33&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGA:2-PHOSPHOGLYCOLIC+ACID'>PGA</scene></td></tr>
-
[[Category: Isome, Y]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7thi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7thi OCA], [https://pdbe.org/7thi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7thi RCSB], [https://www.ebi.ac.uk/pdbsum/7thi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7thi ProSAT]</span></td></tr>
-
[[Category: Sage, D]]
+
</table>
-
[[Category: Yang, Y]]
+
== Disease ==
-
[[Category: Wright, K]]
+
[https://www.uniprot.org/uniprot/PMGE_HUMAN PMGE_HUMAN] Defects in BPGM are the cause of bisphosphoglycerate mutase deficiency (BPGMD) [MIM:[https://omim.org/entry/222800 222800]. A disease characterized by hemolytic anemia, splenomegaly, cholelithiasis and cholecystitis.<ref>PMID:2542247</ref> <ref>PMID:1421379</ref> <ref>PMID:15054810</ref>
-
[[Category: Christodoulou, C]]
+
== Function ==
-
[[Category: Clark, K.L]]
+
[https://www.uniprot.org/uniprot/PMGE_HUMAN PMGE_HUMAN] Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.1) and phosphatase (EC 3.1.3.13) activities.
-
[[Category: Kulathila, R]]
+
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Christodoulou C]]
 +
[[Category: Clark KL]]
 +
[[Category: Isome Y]]
 +
[[Category: Kulathila R]]
 +
[[Category: Sage D]]
 +
[[Category: Wright K]]
 +
[[Category: Yang Y]]

Current revision

Human Bisphosphoglycerate Mutase complexed with 2-phosphoglycolate

PDB ID 7thi

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/7thi"
Personal tools