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2ja2

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Current revision (14:40, 13 December 2023) (edit) (undo)
 
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<StructureSection load='2ja2' size='340' side='right'caption='[[2ja2]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='2ja2' size='340' side='right'caption='[[2ja2]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ja2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JA2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JA2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ja2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JA2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JA2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glutamate--tRNA_ligase Glutamate--tRNA ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.17 6.1.1.17] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ja2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ja2 OCA], [https://pdbe.org/2ja2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ja2 RCSB], [https://www.ebi.ac.uk/pdbsum/2ja2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ja2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ja2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ja2 OCA], [https://pdbe.org/2ja2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ja2 RCSB], [https://www.ebi.ac.uk/pdbsum/2ja2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ja2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/SYE_MYCTU SYE_MYCTU]] Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity).
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[https://www.uniprot.org/uniprot/SYE_MYCTU SYE_MYCTU] Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Glutamate--tRNA ligase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Myctu]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Bartunik, H D]]
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[[Category: Bartunik HD]]
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[[Category: Bourenkov, G P]]
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[[Category: Bourenkov GP]]
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[[Category: Bruning, M]]
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[[Category: Bruning M]]
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[[Category: Shkolnaya, L A]]
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[[Category: Shkolnaya LA]]
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[[Category: Strizhov, N]]
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[[Category: Strizhov N]]
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[[Category: Aminoacyl-trna synthetase]]
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[[Category: Atp-binding]]
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[[Category: Ligase]]
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[[Category: Non-discriminating glutamyl-trna aminoacylation]]
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[[Category: Nucleotide-binding]]
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[[Category: Protein biosynthesis]]
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Current revision

Mycobacterium tuberculosis glutamyl-tRNA synthetase

PDB ID 2ja2

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