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3bz7

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Current revision (12:18, 30 August 2023) (edit) (undo)
 
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<StructureSection load='3bz7' size='340' side='right'caption='[[3bz7]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3bz7' size='340' side='right'caption='[[3bz7]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3bz7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_11735 Atcc 11735]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BZ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BZ7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3bz7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BZ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BZ7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BL4:(3AS)-3A-HYDROXY-5-METHYL-1-PHENYL-1,2,3,3A-TETRAHYDRO-4H-PYRROLO[2,3-B]QUINOLIN-4-ONE'>BL4</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=VO4:VANADATE+ION'>VO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1yv3|1yv3]], [[3bz8|3bz8]], [[3bz9|3bz9]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BL4:(3AS)-3A-HYDROXY-5-METHYL-1-PHENYL-1,2,3,3A-TETRAHYDRO-4H-PYRROLO[2,3-B]QUINOLIN-4-ONE'>BL4</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=VO4:VANADATE+ION'>VO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mhcA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=44689 ATCC 11735])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bz7 OCA], [https://pdbe.org/3bz7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bz7 RCSB], [https://www.ebi.ac.uk/pdbsum/3bz7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bz7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bz7 OCA], [https://pdbe.org/3bz7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bz7 RCSB], [https://www.ebi.ac.uk/pdbsum/3bz7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bz7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MYS2_DICDI MYS2_DICDI]] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.
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[https://www.uniprot.org/uniprot/MYS2_DICDI MYS2_DICDI] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 11735]]
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[[Category: Dictyostelium discoideum]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Allingham, J S]]
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[[Category: Allingham JS]]
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[[Category: Rayment, I]]
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[[Category: Rayment I]]
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[[Category: Actin-binding]]
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[[Category: Atp-binding]]
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[[Category: Blebbistatin analogue]]
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[[Category: Calmodulin-binding]]
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[[Category: Coiled coil]]
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[[Category: Contractile protein]]
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[[Category: Cytoplasm]]
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[[Category: Methylation]]
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[[Category: Motor domain]]
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[[Category: Motor protein]]
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[[Category: Myosin inhibitor]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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Current revision

Crystal Structures of (S)-(-)-Blebbistatin Analogs bound to Dictyostelium discoideum myosin II

PDB ID 3bz7

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OCA

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