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7qu4
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Recombinant Human Fetal Hemoglobin mutant - alpha subunit mutations K11E,K56E,N78D,K90E== | |
| + | <StructureSection load='7qu4' size='340' side='right'caption='[[7qu4]], [[Resolution|resolution]] 1.66Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7qu4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QU4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QU4 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qu4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qu4 OCA], [https://pdbe.org/7qu4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qu4 RCSB], [https://www.ebi.ac.uk/pdbsum/7qu4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qu4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/HBG2_HUMAN HBG2_HUMAN] Hereditary persistence of fetal hemoglobin - beta-thalassemia;Hereditary persistence of fetal hemoglobin - sickle cell disease;Hemoglobinopathy Toms River. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HBG2_HUMAN HBG2_HUMAN] Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. | ||
| - | + | ==See Also== | |
| - | + | *[[Hemoglobin 3D structures|Hemoglobin 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bulow L]] | ||
| + | [[Category: Kettisen K]] | ||
| + | [[Category: Nyblom M]] | ||
Current revision
Recombinant Human Fetal Hemoglobin mutant - alpha subunit mutations K11E,K56E,N78D,K90E
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