7wnh
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Nurr1 binding to NBRE== | |
| - | + | <StructureSection load='7wnh' size='340' side='right'caption='[[7wnh]], [[Resolution|resolution]] 3.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7wnh]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WNH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WNH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wnh OCA], [https://pdbe.org/7wnh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wnh RCSB], [https://www.ebi.ac.uk/pdbsum/7wnh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wnh ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NR4A2_HUMAN NR4A2_HUMAN] Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Guo Y]] | ||
| + | [[Category: Liu J]] | ||
| + | [[Category: Wang N]] | ||
| + | [[Category: Xu T]] | ||
| + | [[Category: Zhao M]] | ||
Current revision
Crystal structure of Nurr1 binding to NBRE
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Categories: Homo sapiens | Large Structures | Synthetic construct | Guo Y | Liu J | Wang N | Xu T | Zhao M
