7dy7
From Proteopedia
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==Discovery of Novel Small-molecule Inhibitors of PD-1/PD-L1 Axis that Promotes PD-L1 Internalization and Degradation== | ==Discovery of Novel Small-molecule Inhibitors of PD-1/PD-L1 Axis that Promotes PD-L1 Internalization and Degradation== | ||
| - | <StructureSection load='7dy7' size='340' side='right'caption='[[7dy7]]' scene=''> | + | <StructureSection load='7dy7' size='340' side='right'caption='[[7dy7]], [[Resolution|resolution]] 2.42Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DY7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DY7 FirstGlance]. <br> | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DY7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DY7 FirstGlance]. <br> | ||
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dy7 OCA], [https://pdbe.org/7dy7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dy7 RCSB], [https://www.ebi.ac.uk/pdbsum/7dy7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dy7 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.42Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HOU:2-[[3-[[5-(2-methyl-3-phenyl-phenyl)-1,3,4-oxadiazol-2-yl]amino]phenyl]methylamino]ethanol'>HOU</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dy7 OCA], [https://pdbe.org/7dy7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dy7 RCSB], [https://www.ebi.ac.uk/pdbsum/7dy7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dy7 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
__TOC__ | __TOC__ | ||
Current revision
Discovery of Novel Small-molecule Inhibitors of PD-1/PD-L1 Axis that Promotes PD-L1 Internalization and Degradation
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Categories: Large Structures | Cheng Y | Jiang S | Lu ML | Wang TY | Xiao YB
