This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7oon
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==The X-ray structure of heme-bound murine HEBP1== | ==The X-ray structure of heme-bound murine HEBP1== | ||
| - | <StructureSection load='7oon' size='340' side='right'caption='[[7oon]]' scene=''> | + | <StructureSection load='7oon' size='340' side='right'caption='[[7oon]], [[Resolution|resolution]] 2.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OON FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7oon]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OON FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oon OCA], [https://pdbe.org/7oon PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oon RCSB], [https://www.ebi.ac.uk/pdbsum/7oon PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oon ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oon OCA], [https://pdbe.org/7oon PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oon RCSB], [https://www.ebi.ac.uk/pdbsum/7oon PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oon ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HEBP1_MOUSE HEBP1_MOUSE] May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities.<ref>PMID:12413491</ref> <ref>PMID:16905545</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
[[Category: Birck C]] | [[Category: Birck C]] | ||
[[Category: Goodfellow BJ]] | [[Category: Goodfellow BJ]] | ||
[[Category: McEwen AG]] | [[Category: McEwen AG]] | ||
[[Category: Poussin-Courmontagne P]] | [[Category: Poussin-Courmontagne P]] | ||
Current revision
The X-ray structure of heme-bound murine HEBP1
| |||||||||||
