Sandbox Test M

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==Your Heading Here (maybe something like 'Structure')==
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==AlphaFold2 Model of Sars-CoV-2 Protein M==
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<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='90/902730/Sars-cov-2_protein_m/2'>
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<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='90/902730/Sars-cov-2_protein_m/3'>
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This is a default text for your page '''Sandbox Test M'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
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{{Theoretical_model}} {{Template:ModelConfidence}}
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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To the right is an '''[[AlphaFold]]2''' 3D model of SARS CoV-2 Protein (UniProt ID: QHD43419) color coded by the pLDDT scores. It corresponds to the highest ranked model in terms of the pLDDT confidence scores, ''i.e.'', model 4<ref name="MIT_ColabFold"> MIT ColabFold https://colab.research.google.com/github/sokrypton/ColabFold/blob/main/beta/AlphaFold2_advanced.ipynb </ref>.
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== Function ==
== Function ==
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'''Protein M'''
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Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.<ref>[https://zhanglab.ccmb.med.umich.edu/COVID-19/ Modeling of the SARS-COV-2 Genome]</ref><ref>pmid 32200634</ref>]
== Disease ==
== Disease ==
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== Relevance ==
== Relevance ==
== Structural highlights ==
== Structural highlights ==
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[[Image:SARSCoV2_protein_M_250.gif|250px|left|thumb|'''Morph''' of the top 5 ranked [[AlphaFold]]2 models of '''SARS-CoV-2 Protein M''', ''rainbow'' color coded N-C<ref name="MIT_ColabFold"/>.]]
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
 
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== See also ==
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[[Coronavirus_Disease 2019 (COVID-19)]]
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__NOTOC__
</StructureSection>
</StructureSection>
== References ==
== References ==
<references/>
<references/>

Current revision

AlphaFold2 Model of Sars-CoV-2 Protein M

Caption for this structure

Drag the structure with the mouse to rotate

References

  1. ↑ 1.0 1.1 MIT ColabFold https://colab.research.google.com/github/sokrypton/ColabFold/blob/main/beta/AlphaFold2_advanced.ipynb
  2. ↑ Modeling of the SARS-COV-2 Genome
  3. ↑ Zhang C, Zheng W, Huang X, Bell EW, Zhou X, Zhang Y. Protein Structure and Sequence Reanalysis of 2019-nCoV Genome Refutes Snakes as Its Intermediate Host and the Unique Similarity between Its Spike Protein Insertions and HIV-1. J Proteome Res. 2020 Apr 3;19(4):1351-1360. doi: 10.1021/acs.jproteome.0c00129., Epub 2020 Mar 24. PMID:32200634 doi:http://dx.doi.org/10.1021/acs.jproteome.0c00129
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