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Prolyl hydroxylase domain
From Proteopedia
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<ref>Rosen M D, Venkatesan H, Peltier H M, Bembenek S D, Kanelakis K C, Zhao L X, Leonard B E, Hocutt F M, Wu X, Palomino H L, Brondtetter T I, Haugh P V, Cagnon L, Yan W, Liotta L A, Young A, Mirzadegan T, Shankley N P, Barrett T D, Rabinowitz M H. Benzimidazole-2-pyrazole HIF Prolyl 4-Hydroxylase Inhibitors as Oral Erythropoietin Secretagogues. ACS Medicinal Chemical Letters. 2010 Oct 5.</ref> For more detalis see [[Molecular Playground/Prolyl Hydroxylase Domain (PHD) Enzyme]]. | <ref>Rosen M D, Venkatesan H, Peltier H M, Bembenek S D, Kanelakis K C, Zhao L X, Leonard B E, Hocutt F M, Wu X, Palomino H L, Brondtetter T I, Haugh P V, Cagnon L, Yan W, Liotta L A, Young A, Mirzadegan T, Shankley N P, Barrett T D, Rabinowitz M H. Benzimidazole-2-pyrazole HIF Prolyl 4-Hydroxylase Inhibitors as Oral Erythropoietin Secretagogues. ACS Medicinal Chemical Letters. 2010 Oct 5.</ref> For more detalis see [[Molecular Playground/Prolyl Hydroxylase Domain (PHD) Enzyme]]. | ||
| - | </StructureSection> | ||
== 3D Structures of prolyl hydroxylase domain == | == 3D Structures of prolyl hydroxylase domain == | ||
| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | + | [[Polyl hydroxylase domain 3D structures]] | |
| - | **[[5l9r]] - hPHD2 catalytic domain residues 181-426 (mutant) + Mn + 2OG - human<br /> | ||
| - | **[[3hqr]], [[5l9b]] - hPHD2 catalytic domain (mutant) + Mn + HIF 1 α C terminal + 2OG<br /> | ||
| - | **[[5l9v]], [[5la9]], [[5las]] - hPHD2 catalytic domain (mutant) + Mn + HIF NODD domain + 2OG<br /> | ||
| - | **[[4bqw]], [[4bqx]], [[4bqy]] - hPHD2 catalytic domain + Mn + quinolin derivative<br /> | ||
| - | **[[6st3]] - hPHD2 catalytic domain + Mn + pyrimidin derivative<br /> | ||
| - | **[[6yvt]] - hPHD2 catalytic domain + Mn + pyridin derivative<br /> | ||
| - | **[[6qgv]], [[5a3u]], [[6st3]], [[6yvt]], [[6zbn]], [[6zbo]] - hPHD2 catalytic domain + Mn + inhibitor<br /> | ||
| - | **[[5ox6]], [[6ox5]] - hPHD2 catalytic domain + Mn + drug<br /> | ||
| - | **[[5lat]], [[5lb6]], [[5lbb]], [[5lbc]], [[5lbe]], [[5lbf]], [[4uwd]] - hPHD2 catalytic domain (mutant) + Mn + quinolin derivative<br /> | ||
| - | **[[6yvx]], [[6yvz]] - hPHD2 catalytic domain + Mn + peptide<br /> | ||
| - | **[[6yw3]] - hPHD2 catalytic domain + Mn + peptide + oxalylglycine<br /> | ||
| - | **[[6yw1]], [[6yw2]], [[6yw4]] - hPHD2 catalytic domain (mutant) + Mn + peptide + oxalylglycine<br /> | ||
| - | |||
| - | *Prolyl hydroxylase domain containing other metal ions | ||
| - | |||
| - | **[[2y33]] – hPHD2 catalytic domain residues + Zn + quinolin derivative – human<br /> | ||
| - | **[[3ouh]], [[3oui]], [[5v18]], [[6nmq]], [[6yvw]], [[6yw0]] - hPHD2 catalytic domain + Fe + inhibitor<br /> | ||
| - | **[[4kbz]] - hPHD2 catalytic domain (mutant) + Fe + inhibitor<br /> | ||
| - | **[[4jzr]] - hPHD2 catalytic domain + Ni + inhibitor<br /> | ||
| - | **[[3ouj]] - hPHD2 catalytic domain + Fe + 2OG<br /> | ||
| - | **[[3hqu]] - hPHD2 catalytic domain + Fe + HIF 1 α C terminal + quinolin derivative<br /> | ||
| - | **[[2hbt]], [[2hbu]], [[2g19]], [[2g1m]], [[2y34]], [[4bqi]] - hPHD2 catalytic domain + Fe + quinolin derivative<br /> | ||
| - | **[[5v18]] - hPHD2 catalytic domain + Fe + pyridin derivative<br /> | ||
| - | **[[5v1b]] - hPHD1 catalytic domain + Fe + inhibitor<br /> | ||
| - | **[[6nmq]] - hPHD2 catalytic domain + Fe + inhibitor<br /> | ||
| - | }} | ||
==References== | ==References== | ||
<references/> | <references/> | ||
| + | </StructureSection> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
<br /> | <br /> | ||
Created with the participation of [[User:Andrew Winslow|Andrew Winslow]]. | Created with the participation of [[User:Andrew Winslow|Andrew Winslow]]. | ||
Current revision
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Created with the participation of Andrew Winslow.
