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7wq4
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Galanin-bound galanin receptor 2 in complex with Gq== | |
| + | <StructureSection load='7wq4' size='340' side='right'caption='[[7wq4]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7wq4]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Rattus Rattus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WQ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WQ4 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wq4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wq4 OCA], [https://pdbe.org/7wq4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wq4 RCSB], [https://www.ebi.ac.uk/pdbsum/7wq4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wq4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GALR2_HUMAN GALR2_HUMAN] Receptor for the hormone galanin and GALP. Receptor for the hormone spexin-1 (PubMed:24517231). The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i)).<ref>PMID:24517231</ref> <ref>PMID:25691535</ref> <ref>PMID:9480833</ref> <ref>PMID:9685625</ref> <ref>PMID:9832121</ref> <ref>PMID:9880084</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Transducin 3D structures|Transducin 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bos taurus]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Lama glama]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rattus]] | ||
| + | [[Category: Duan J]] | ||
| + | [[Category: Jiang Y]] | ||
| + | [[Category: Shen DD]] | ||
| + | [[Category: Xu HE]] | ||
| + | [[Category: Zhang Y]] | ||
Current revision
Galanin-bound galanin receptor 2 in complex with Gq
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Categories: Bos taurus | Homo sapiens | Lama glama | Large Structures | Rattus | Duan J | Jiang Y | Shen DD | Xu HE | Zhang Y
