7sq9
From Proteopedia
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==Cryo-EM structure of mouse temsirolimus/PI(3,5)P2-bound TRPML1 channel at 2.11 Angstrom resolution== | ==Cryo-EM structure of mouse temsirolimus/PI(3,5)P2-bound TRPML1 channel at 2.11 Angstrom resolution== | ||
| - | <StructureSection load='7sq9' size='340' side='right'caption='[[7sq9]]' scene=''> | + | <StructureSection load='7sq9' size='340' side='right'caption='[[7sq9]], [[Resolution|resolution]] 2.11Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SQ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SQ9 FirstGlance]. <br> | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SQ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SQ9 FirstGlance]. <br> | ||
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sq9 OCA], [https://pdbe.org/7sq9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sq9 RCSB], [https://www.ebi.ac.uk/pdbsum/7sq9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sq9 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.11Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A4I:(1R,2R,4S)-4-{(2R)-2-[(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,30S,34aS)-9,27-dihydroxy-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-1,5,11,28,29-pentaoxo-1,4,5,6,9,10,11,12,13,14,21,22,23,24,25,26,27,28,29,31,32,33,34,34a-tetracosahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontin-3-yl]propyl}-2-methoxycyclohexyl+3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate'>A4I</scene>, <scene name='pdbligand=EUJ:(2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl+dioctanoate'>EUJ</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sq9 OCA], [https://pdbe.org/7sq9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sq9 RCSB], [https://www.ebi.ac.uk/pdbsum/7sq9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sq9 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
__TOC__ | __TOC__ | ||
Current revision
Cryo-EM structure of mouse temsirolimus/PI(3,5)P2-bound TRPML1 channel at 2.11 Angstrom resolution
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Categories: Large Structures | Gan N | Han Y | Jiang Y
