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3csw

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Current revision (11:30, 1 February 2023) (edit) (undo)
 
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<StructureSection load='3csw' size='340' side='right'caption='[[3csw]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='3csw' size='340' side='right'caption='[[3csw]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3csw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thema Thema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CSW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3csw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CSW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TM0831, ilvE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 THEMA])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Branched-chain-amino-acid_transaminase Branched-chain-amino-acid transaminase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.42 2.6.1.42] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3csw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3csw OCA], [https://pdbe.org/3csw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3csw RCSB], [https://www.ebi.ac.uk/pdbsum/3csw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3csw ProSAT], [https://www.topsan.org/Proteins/JCSG/3csw TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3csw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3csw OCA], [https://pdbe.org/3csw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3csw RCSB], [https://www.ebi.ac.uk/pdbsum/3csw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3csw ProSAT], [https://www.topsan.org/Proteins/JCSG/3csw TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ILVE_THEMA ILVE_THEMA]] Acts on leucine, isoleucine and valine.
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[https://www.uniprot.org/uniprot/ILVE_THEMA ILVE_THEMA] Acts on leucine, isoleucine and valine.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Branched-chain-amino-acid transaminase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Thema]]
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[[Category: Thermotoga maritima MSB8]]
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[[Category: Structural genomic]]
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[[Category: Amino-acid biosynthesis]]
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[[Category: Branched-chain amino acid biosynthesis]]
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[[Category: Jcsg]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Putative branched-chain amino acid aminotransferase]]
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[[Category: Pyridoxal phosphate]]
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[[Category: Tm0831]]
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[[Category: Transferase]]
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Current revision

Crystal structure of a putative branched-chain amino acid aminotransferase (TM0831) from Thermotoga maritima at 2.15 A resolution

PDB ID 3csw

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