This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3d9y
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='3d9y' size='340' side='right'caption='[[3d9y]], [[Resolution|resolution]] 1.65Å' scene=''> | <StructureSection load='3d9y' size='340' side='right'caption='[[3d9y]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3d9y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3d9y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D9Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D9Y FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d9y OCA], [https://pdbe.org/3d9y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d9y RCSB], [https://www.ebi.ac.uk/pdbsum/3d9y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d9y ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d9y OCA], [https://pdbe.org/3d9y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d9y RCSB], [https://www.ebi.ac.uk/pdbsum/3d9y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d9y ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/PROF_SCHPO PROF_SCHPO] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. In S.pombe, it is essential for cytokinesis. | |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 27: | Line 26: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Cbs 356]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Schizosaccharomyces pombe]] |
| - | [[Category: | + | [[Category: Ezezika OC]] |
| - | [[Category: | + | [[Category: Nolen BJ]] |
| - | [[Category: | + | [[Category: Pollard TD]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of Profilin from Schizosaccharomyces pombe
| |||||||||||
