SARS-CoV-2 protein M

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:53, 14 February 2022) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='84/842059/Sars-cov-2_protein_m/2'>
<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='84/842059/Sars-cov-2_protein_m/2'>
{{Theoretical_model}} {{Template:ModelConfidence}}
{{Theoretical_model}} {{Template:ModelConfidence}}
-
To the right is an '''[[AlphaFold]]2''' 3D model of SARS CoV-2 Protein (UniProt ID: QHD43419) color coded by the pLDDT scores. It corresponds to the highest ranked model in terms of the pLDDT confidence scores, ''i.e.'', model 4<ref name="MIT_ColabFold">[https://colab.research.google.com/github/sokrypton/ColabFold/blob/main/beta/AlphaFold2_advanced.ipynb MIT ColabFold]</ref>.
+
To the right is an '''[[AlphaFold]]2''' 3D model of SARS CoV-2 Protein M (length=222 amino acids, [https://www.uniprot.org/uniprot/P0DTC5 UniProt ID: P0DTC5]) color coded by the pLDDT scores. It corresponds to the highest ranked model in terms of the pLDDT confidence scores, ''i.e.'', model 4<ref name="MIT_ColabFold">[https://colab.research.google.com/github/sokrypton/ColabFold/blob/main/beta/AlphaFold2_advanced.ipynb MIT ColabFold]</ref>.
== Function ==
== Function ==
Line 9: Line 9:
== Function ==
== Function ==
'''Protein M'''
'''Protein M'''
-
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.<ref name="Zhang_Lab">[https://zhanglab.ccmb.med.umich.edu/COVID-19/ Modeling of the SARS-COV-2 Genome]</ref>
+
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.<ref name="MIT_ColabFold"/><ref name="Zhang_Lab">[https://zhanglab.ccmb.med.umich.edu/COVID-19/ Modeling of the SARS-COV-2 Genome]</ref>
-
<ref>pmid 32200634</ref>
+
<ref>pmid 32200634</ref>.
== Disease ==
== Disease ==
Line 41: Line 41:
== See also ==
== See also ==
-
[[Coronavirus_Disease 2019 (COVID-19)]]
+
[[Coronavirus_Disease 2019 (COVID-19)]]<br>
 +
[[SARS-CoV-2_virus_proteins]]<br>
 +
[[COVID-19 AlphaFold2 Models]]
__NOTOC__
__NOTOC__
</StructureSection>
</StructureSection>
== References ==
== References ==
<references/>
<references/>

Current revision

Caption for this structure

Drag the structure with the mouse to rotate

References

  1. ↑ 1.0 1.1 1.2 MIT ColabFold
  2. ↑ Modeling of the SARS-COV-2 Genome
  3. ↑ Zhang C, Zheng W, Huang X, Bell EW, Zhou X, Zhang Y. Protein Structure and Sequence Reanalysis of 2019-nCoV Genome Refutes Snakes as Its Intermediate Host and the Unique Similarity between Its Spike Protein Insertions and HIV-1. J Proteome Res. 2020 Apr 3;19(4):1351-1360. doi: 10.1021/acs.jproteome.0c00129., Epub 2020 Mar 24. PMID:32200634 doi:http://dx.doi.org/10.1021/acs.jproteome.0c00129

Proteopedia Page Contributors and Editors (what is this?)

Joel L. Sussman, Jaime Prilusky

Retrieved from "http://52.214.119.220/wiki/index.php/SARS-CoV-2_protein_M"
Personal tools