7tq5
From Proteopedia
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==Structure of SARS-CoV-2 3CL protease in complex with the cyclopropane based inhibitor 11c== | ==Structure of SARS-CoV-2 3CL protease in complex with the cyclopropane based inhibitor 11c== | ||
| - | <StructureSection load='7tq5' size='340' side='right'caption='[[7tq5]]' scene=''> | + | <StructureSection load='7tq5' size='340' side='right'caption='[[7tq5]], [[Resolution|resolution]] 1.65Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TQ5 FirstGlance]. <br> | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TQ5 FirstGlance]. <br> | ||
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tq5 OCA], [https://pdbe.org/7tq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tq5 RCSB], [https://www.ebi.ac.uk/pdbsum/7tq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tq5 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IRW:(1S,2S)-1-hydroxy-2-{[N-({[(1R,2R)-2-(4-methoxyphenyl)cyclopropyl]methoxy}carbonyl)-L-leucyl]amino}-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic+acid'>IRW</scene>, <scene name='pdbligand=ITX:(1R,2S)-1-hydroxy-2-{[N-({[(1R,2R)-2-(4-methoxyphenyl)cyclopropyl]methoxy}carbonyl)-L-leucyl]amino}-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic+acid'>ITX</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tq5 OCA], [https://pdbe.org/7tq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tq5 RCSB], [https://www.ebi.ac.uk/pdbsum/7tq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tq5 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
__TOC__ | __TOC__ | ||
Current revision
Structure of SARS-CoV-2 3CL protease in complex with the cyclopropane based inhibitor 11c
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Categories: Large Structures | Battaile KP | Chamandi SD | Chang KO | Groutas WC | Kim Y | Liu L | Lovell S | Madden TK | Nguyen HN | Picard HR | Thruman HA
