3doa
From Proteopedia
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<StructureSection load='3doa' size='340' side='right'caption='[[3doa]], [[Resolution|resolution]] 2.81Å' scene=''> | <StructureSection load='3doa' size='340' side='right'caption='[[3doa]], [[Resolution|resolution]] 2.81Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3doa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3doa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DOA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DOA FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.81Å</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3doa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3doa OCA], [https://pdbe.org/3doa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3doa RCSB], [https://www.ebi.ac.uk/pdbsum/3doa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3doa ProSAT], [https://www.topsan.org/Proteins/MCSG/3doa TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3doa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3doa OCA], [https://pdbe.org/3doa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3doa RCSB], [https://www.ebi.ac.uk/pdbsum/3doa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3doa ProSAT], [https://www.topsan.org/Proteins/MCSG/3doa TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A0H3JV08_STAAM A0A0H3JV08_STAAM] Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.[HAMAP-Rule:MF_00844] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Staphylococcus aureus subsp. aureus Mu50]] |
| - | [[Category: Freeman | + | [[Category: Freeman L]] |
| - | [[Category: Joachimiak | + | [[Category: Joachimiak A]] |
| - | + | [[Category: Wu R]] | |
| - | [[Category: Wu | + | [[Category: Zhang R]] |
| - | [[Category: Zhang | + | |
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Current revision
The crystal structure of the fibrinogen binding protein from Staphylococcus aureus
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