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7r2m
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7r2m is ON HOLD Authors: Carrasco, K., Cousido Siah, A., Gogl, G., Betzi, S., McEwen, A., Kostmann, C., Trave, G. Description: SYNJ2BP complex with...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==SYNJ2BP complex with a synthetic Vangl2 peptide (9mer).== | |
| - | + | <StructureSection load='7r2m' size='340' side='right'caption='[[7r2m]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7r2m]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7R2M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7R2M FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7r2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7r2m OCA], [https://pdbe.org/7r2m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7r2m RCSB], [https://www.ebi.ac.uk/pdbsum/7r2m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7r2m ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: Gogl | + | [https://www.uniprot.org/uniprot/A0A4W2GEM6_BOBOX A0A4W2GEM6_BOBOX] Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.[ARBA:ARBA00003833][https://www.uniprot.org/uniprot/SYJ2B_HUMAN SYJ2B_HUMAN] |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Betzi S]] | ||
| + | [[Category: Carrasco K]] | ||
| + | [[Category: Cousido Siah A]] | ||
| + | [[Category: Gogl G]] | ||
| + | [[Category: Kostmann C]] | ||
| + | [[Category: McEwen A]] | ||
| + | [[Category: Trave G]] | ||
Current revision
SYNJ2BP complex with a synthetic Vangl2 peptide (9mer).
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Categories: Homo sapiens | Large Structures | Betzi S | Carrasco K | Cousido Siah A | Gogl G | Kostmann C | McEwen A | Trave G
