7wtt

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(New page: '''Unreleased structure''' The entry 7wtt is ON HOLD Authors: Cheng, J., Lau, B., Thoms, M., Ameismeier, M., Berninghausen, O., Hurt, E., Beckmann, R. Description: Cryo-EM structure of...)
Current revision (19:23, 19 October 2022) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 7wtt is ON HOLD
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==Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (with CK1)==
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<StructureSection load='7wtt' size='340' side='right'caption='[[7wtt]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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Authors: Cheng, J., Lau, B., Thoms, M., Ameismeier, M., Berninghausen, O., Hurt, E., Beckmann, R.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7wtt]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WTT FirstGlance]. <br>
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Description: Cryo-EM structure of a human pre-40S ribosomal subunit -State RRP12-A1 (with CK1)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G7M:N7-METHYL-GUANOSINE-5-MONOPHOSPHATE'>G7M</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wtt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wtt OCA], [https://pdbe.org/7wtt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wtt RCSB], [https://www.ebi.ac.uk/pdbsum/7wtt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wtt ProSAT]</span></td></tr>
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[[Category: Cheng, J]]
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</table>
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[[Category: Hurt, E]]
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== Disease ==
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[[Category: Berninghausen, O]]
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[https://www.uniprot.org/uniprot/RS17_HUMAN RS17_HUMAN] Blackfan-Diamond disease. Diamond-Blackfan anemia 4 (DBA4) [MIM:[https://omim.org/entry/612527 612527]: A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of developing leukemia. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:17647292</ref> <ref>PMID:19061985</ref>
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[[Category: Lau, B]]
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== Function ==
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[[Category: Ameismeier, M]]
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[https://www.uniprot.org/uniprot/RS17_HUMAN RS17_HUMAN]
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[[Category: Beckmann, R]]
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== References ==
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[[Category: Thoms, M]]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Ameismeier M]]
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[[Category: Beckmann R]]
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[[Category: Berninghausen O]]
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[[Category: Cheng J]]
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[[Category: Hurt E]]
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[[Category: Lau B]]
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[[Category: Thoms M]]

Current revision

Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (with CK1)

PDB ID 7wtt

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