This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


7kpr

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:29, 18 October 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='7kpr' size='340' side='right'caption='[[7kpr]], [[Resolution|resolution]] 3.09&Aring;' scene=''>
<StructureSection load='7kpr' size='340' side='right'caption='[[7kpr]], [[Resolution|resolution]] 3.09&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[7kpr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KPR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KPR FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[7kpr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KPR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KPR FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.09&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PPM1H, ARHCL1, KIAA1157, URCC2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Phosphoprotein_phosphatase Phosphoprotein phosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.16 3.1.3.16] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kpr OCA], [https://pdbe.org/7kpr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kpr RCSB], [https://www.ebi.ac.uk/pdbsum/7kpr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kpr ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kpr OCA], [https://pdbe.org/7kpr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kpr RCSB], [https://www.ebi.ac.uk/pdbsum/7kpr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kpr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/PPM1H_HUMAN PPM1H_HUMAN]] Dephosphorylates CDKN1B at 'Thr-187', thus removing a signal for proteasomal degradation.<ref>PMID:22586611</ref>
+
[https://www.uniprot.org/uniprot/PPM1H_HUMAN PPM1H_HUMAN] Dephosphorylates CDKN1B at 'Thr-187', thus removing a signal for proteasomal degradation.<ref>PMID:22586611</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 24: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Phosphoprotein phosphatase]]
+
[[Category: Khan AR]]
-
[[Category: Khan, A R]]
+
[[Category: Waschbusch D]]
-
[[Category: Waschbusch, D]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Membrane trafficking]]
+
-
[[Category: Ppm family]]
+
-
[[Category: Rab gtpase]]
+

Current revision

Structure of wild-type PPM1H phosphatase at 3.1 Angstrom resolution

PDB ID 7kpr

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/7kpr"
Personal tools