2mjq

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==Structure of antimicrobial peptide anoplin in DPC micelles==
==Structure of antimicrobial peptide anoplin in DPC micelles==
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<StructureSection load='2mjq' size='340' side='right'caption='[[2mjq]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2mjq' size='340' side='right'caption='[[2mjq]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2mjq]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MJQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2mjq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Anoplius_samariensis Anoplius samariensis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MJQ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPV:DODECYL+2-(TRIMETHYLAMMONIO)ETHYL+PHOSPHATE'>DPV</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPV:DODECYL+2-(TRIMETHYLAMMONIO)ETHYL+PHOSPHATE'>DPV</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2mjr|2mjr]], [[2mjs|2mjs]], [[2mjt|2mjt]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mjq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mjq OCA], [https://pdbe.org/2mjq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mjq RCSB], [https://www.ebi.ac.uk/pdbsum/2mjq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mjq ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mjq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mjq OCA], [https://pdbe.org/2mjq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mjq RCSB], [https://www.ebi.ac.uk/pdbsum/2mjq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mjq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ANOP_ANOSM ANOP_ANOSM]] Exhibits potent activity in stimulating degranulation from rat peritoneal mast cells but not from RBL-2H3 cells. Exhibits broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria. Has no hemolytic activity towards human erythrocytes.<ref>PMID:11738089</ref>
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[https://www.uniprot.org/uniprot/ANOP_ANOSM ANOP_ANOSM] Exhibits potent activity in stimulating degranulation from rat peritoneal mast cells but not from RBL-2H3 cells. Exhibits broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria. Has no hemolytic activity towards human erythrocytes.<ref>PMID:11738089</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Anoplius samariensis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Poulsen, T J]]
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[[Category: Poulsen TJ]]
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[[Category: Uggerhoej, L]]
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[[Category: Uggerhoej L]]
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[[Category: Wimmer, R]]
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[[Category: Wimmer R]]
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[[Category: Amphipathic helix]]
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[[Category: Antimicrobial protein]]
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Current revision

Structure of antimicrobial peptide anoplin in DPC micelles

PDB ID 2mjq

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