3ee4

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Current revision (01:45, 21 November 2024) (edit) (undo)
 
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<StructureSection load='3ee4' size='340' side='right'caption='[[3ee4]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3ee4' size='340' side='right'caption='[[3ee4]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ee4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EE4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EE4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ee4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EE4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EE4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MN3:MANGANESE+(III)+ION'>MN3</scene>, <scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nrdB, Rv0233 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MN3:MANGANESE+(III)+ION'>MN3</scene>, <scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ee4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ee4 OCA], [https://pdbe.org/3ee4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ee4 RCSB], [https://www.ebi.ac.uk/pdbsum/3ee4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ee4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ee4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ee4 OCA], [https://pdbe.org/3ee4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ee4 RCSB], [https://www.ebi.ac.uk/pdbsum/3ee4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ee4 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
 
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[[https://www.uniprot.org/uniprot/RIR2H_MYCTU RIR2H_MYCTU]] Probable oxidase that might be involved in lipid metabolism.
 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ee/3ee4_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ee/3ee4_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ribonucleoside-diphosphate reductase]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Andersson, C S]]
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[[Category: Andersson CS]]
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[[Category: Hogbom, M]]
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[[Category: Hogbom M]]
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[[Category: Jones, T A]]
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[[Category: Jones TA]]
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[[Category: Carboxylate]]
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[[Category: Cavity]]
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[[Category: Diiron]]
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[[Category: Iron]]
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[[Category: Ligand]]
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[[Category: Manganese]]
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[[Category: Monooxygenase]]
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[[Category: Oxidase]]
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[[Category: Oxidoreductase]]
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[[Category: R2]]
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Current revision

R2-like ligand binding Mn/Fe oxidase from M. tuberculosis

PDB ID 3ee4

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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