This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7yyj
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7yyj is ON HOLD Authors: Dalle Vedove, A., Cazzanelli, G., Lolli, G. Description: Tetragonal crystal structure of YTHDF1 YTH domain (544AVV546 muta...) |
|||
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Tetragonal crystal structure of YTHDF1 YTH domain (544AVV546 mutant)== | |
| - | + | <StructureSection load='7yyj' size='340' side='right'caption='[[7yyj]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7yyj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YYJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YYJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yyj OCA], [https://pdbe.org/7yyj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yyj RCSB], [https://www.ebi.ac.uk/pdbsum/7yyj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yyj ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| + | [https://www.uniprot.org/uniprot/YTHD1_HUMAN YTHD1_HUMAN] Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability.<ref>PMID:24284625</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Cazzanelli G]] | ||
| + | [[Category: Dalle Vedove A]] | ||
| + | [[Category: Lolli G]] | ||
Current revision
Tetragonal crystal structure of YTHDF1 YTH domain (544AVV546 mutant)
| |||||||||||
