7p36

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Current revision (13:00, 1 February 2024) (edit) (undo)
 
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<StructureSection load='7p36' size='340' side='right'caption='[[7p36]], [[Resolution|resolution]] 1.14&Aring;' scene=''>
<StructureSection load='7p36' size='340' side='right'caption='[[7p36]], [[Resolution|resolution]] 1.14&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7p36]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"lactobacillus_kefir"_(sic)_kandler_and_kunath_1983 "lactobacillus kefir" (sic) kandler and kunath 1983]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P36 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P36 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7p36]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lentilactobacillus_kefiri Lentilactobacillus kefiri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P36 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P36 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.14&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">adhR, fabG3, DNL43_05835, LKE01_04370 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=33962 "Lactobacillus kefir" (sic) Kandler and Kunath 1983])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p36 OCA], [https://pdbe.org/7p36 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p36 RCSB], [https://www.ebi.ac.uk/pdbsum/7p36 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p36 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p36 OCA], [https://pdbe.org/7p36 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p36 RCSB], [https://www.ebi.ac.uk/pdbsum/7p36 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p36 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RADH_LENKE RADH_LENKE] NADP-dependent (R)-specific alcohol dehydrogenase (ADH) with a broad substrate specificity, able to catalyze in vitro the stereoselective reduction of several aliphatic and aromatic ketones as well as beta-keto esters to the corresponding enantiomerically pure alcohols.<ref>PMID:26644568</ref>
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==See Also==
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*[[Hydroxysteroid dehydrogenase 3D structures|Hydroxysteroid dehydrogenase 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bischoff, D]]
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[[Category: Lentilactobacillus kefiri]]
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[[Category: Janowski, R]]
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[[Category: Bischoff D]]
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[[Category: Niessing, D]]
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[[Category: Janowski R]]
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[[Category: Walla, B]]
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[[Category: Niessing D]]
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[[Category: Weuster-Botz, D]]
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[[Category: Walla B]]
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[[Category: Alcohol dehydrogenase]]
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[[Category: Weuster-Botz D]]
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[[Category: Ketoreductase]]
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[[Category: Oxidoreductase]]
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[[Category: R-specific]]
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Current revision

X-ray structure of Lactobacillus kefir alcohol dehydrogenase (wild type)

PDB ID 7p36

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