Joseph Gareis/Sandbox 1
From Proteopedia
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| - | = | + | =Dyrk1a= |
| - | <StructureSection load=' | + | <StructureSection load='7FHT' size='350' frame='true' side='right' caption='Crystal structure of DYRK1A' scene='90/905626/Active_site_residues/1'> |
This is a default text for your page '''Joseph Gareis/Sandbox 1'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | This is a default text for your page '''Joseph Gareis/Sandbox 1'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
| - | == | + | == Introduction == |
| + | <ref name:"Cao">PMID:34789874</ref> | ||
| + | [https://www.nature.com/articles/s41586-021-04126-6 Structure, function and pharmacology of human itch GPCRs] | ||
| + | == Structure Overview == | ||
| + | [[Image:C480_ligand_shown.png |400 px|right|thumb|Figure 1. | ||
| + | The coolest image of this protein EVAH!!!]] | ||
| - | == | + | === Domains === |
| + | === DH Box === | ||
| + | <scene name='90/905626/Dh_box/1'>DH box</scene> | ||
| + | === Active site === | ||
| - | == Relevance == | ||
| - | == | + | == Ligands == |
| + | |||
| + | === Agonists === | ||
| + | === Antagonists === | ||
| + | |||
| + | == Relationship to other proteins == | ||
| + | |||
| + | == Clinical Relevance == | ||
| + | |||
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
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== References == | == References == | ||
<references/> | <references/> | ||
| + | |||
| + | == Student contributors == | ||
Current revision
Dyrk1a
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
- ↑ Cao C, Kang HJ, Singh I, Chen H, Zhang C, Ye W, Hayes BW, Liu J, Gumpper RH, Bender BJ, Slocum ST, Krumm BE, Lansu K, McCorvy JD, Kroeze WK, English JG, DiBerto JF, Olsen RHJ, Huang XP, Zhang S, Liu Y, Kim K, Karpiak J, Jan LY, Abraham SN, Jin J, Shoichet BK, Fay JF, Roth BL. Structure, function and pharmacology of human itch GPCRs. Nature. 2021 Dec;600(7887):170-175. doi: 10.1038/s41586-021-04126-6. Epub 2021, Nov 17. PMID:34789874 doi:http://dx.doi.org/10.1038/s41586-021-04126-6
