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1te4

From Proteopedia

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Current revision

Solution structure of MTH187. Ontario Centre for Structural Proteomics target MTH0187_1_111; Northeast Structural Genomics Target TT740

Structural highlights

1te4 is a 1 chain structure with sequence from Methanothermobacter thermautotrophicus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Solution NMR
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

O26289_METTH

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

With the completion of genome sequencing projects, there are a large number of proteins for which we have little or no functional information. Since protein function is closely related to three-dimensional conformation, structural proteomics is one avenue where the role of proteins with unknown function can be investigated. In the present structural project, the structure of MTH187 has been determined by solution-state NMR spectroscopy. This protein of 12.4 kDa is one of the 424 non-membrane proteins that were cloned and purified for the structural proteomic project of Methanobacterium thermoautotrophicum [Christendat, D., Yee, A., Dharamsi, A., Kluger, Y., Gerstein, M., Arrowsmith, C.H. and Edwards, A.M. (2000) Prog. Biophys. Mol. Biol., 73, 339-345]. Methanobacterium thermoautotrophicum is a thermophilic archaeon that grows optimally at 65 degrees C. A particular characteristic of this microorganism is its ability to generate methane from carbon dioxide and hydrogen [Smith, D.R., Doucette-Stamm, L.A., Deloughery, C., Lee, H., Dubois, J., Aldredge, T., Bashirzadeh, R., Blakely, D., Cook, R., Gilbert, K., Harrison, D., Hoang, L., Keagle, P., Lumm, W., Pothier, B., Qiu, D., Spadafora, R., Vicaire, R., Wang, Y., Wierzbowski, J., Gibson, R., Jiwani, N., Caruso, A., Bush, D., Reeve, J. N. et al. (1997) J. Bacteriol., 179, 7135-7155].

MTH187 from Methanobacterium thermoautotrophicum has three HEAT-like repeats.,Julien O, Gignac I, Hutton A, Yee A, Arrowsmith CH, Gagne SM J Biomol NMR. 2006 Jun;35(2):149-54. Epub 2006 May 31. PMID:16819590^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Julien O, Gignac I, Hutton A, Yee A, Arrowsmith CH, Gagne SM. MTH187 from Methanobacterium thermoautotrophicum has three HEAT-like repeats. J Biomol NMR. 2006 Jun;35(2):149-54. Epub 2006 May 31. PMID:16819590 doi:10.1007/s10858-006-0029-3

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1te4"

@@ Line 1: / Line 1: @@
 ==Solution structure of MTH187. Ontario Centre for Structural Proteomics target MTH0187_1_111; Northeast Structural Genomics Target TT740==
-<StructureSection load='1te4' size='340' side='right'caption='[[1te4]], [[NMR_Ensembles_of_Models | 40 NMR models]]' scene=''>
+<StructureSection load='1te4' size='340' side='right'caption='[[1te4]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1te4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"methanobacterium_thermoautotrophicus"_(sic)_zeikus_and_wolfe_1972 "methanobacterium thermoautotrophicus" (sic) zeikus and wolfe 1972]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TE4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TE4 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1te4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TE4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TE4 FirstGlance]. <br>
-</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mt0187 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=145262 "Methanobacterium thermoautotrophicus" (sic) Zeikus and Wolfe 1972])</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1te4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1te4 OCA], [https://pdbe.org/1te4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1te4 RCSB], [https://www.ebi.ac.uk/pdbsum/1te4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1te4 ProSAT], [https://www.topsan.org/Proteins/NESGC/1te4 TOPSAN]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/O26289_METTH O26289_METTH]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 31: / Line 33: @@
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Arrowsmith, C H]]
+[[Category: Methanothermobacter thermautotrophicus]]
-[[Category: Gagne, S M]]
+[[Category: Arrowsmith CH]]
-[[Category: Gignac, I]]
+[[Category: Gagne SM]]
-[[Category: Julien, O]]
+[[Category: Gignac I]]
-[[Category: Structural genomic]]
+[[Category: Julien O]]
-[[Category: Yee, A]]
+[[Category: Yee A]]
-[[Category: Heat-like repeat]]
-[[Category: Methanobacterium thermoautotrophicum]]
-[[Category: Mth187]]
-[[Category: Nesg]]
-[[Category: Ocsp]]
-[[Category: PSI, Protein structure initiative]]
-[[Category: Structural proteomic]]
-[[Category: Unknown function]]

1te4

From Proteopedia

Current revision

Solution structure of MTH187. Ontario Centre for Structural Proteomics target MTH0187_1_111; Northeast Structural Genomics Target TT740

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

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