1wge
From Proteopedia
(Difference between revisions)
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==Solution structure of the mouse DESR1== | ==Solution structure of the mouse DESR1== | ||
| - | <StructureSection load='1wge' size='340' side='right'caption='[[1wge | + | <StructureSection load='1wge' size='340' side='right'caption='[[1wge]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1wge]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1wge]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WGE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WGE FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wge FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wge OCA], [https://pdbe.org/1wge PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wge RCSB], [https://www.ebi.ac.uk/pdbsum/1wge PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wge ProSAT], [https://www.topsan.org/Proteins/RSGI/1wge TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wge FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wge OCA], [https://pdbe.org/1wge PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wge RCSB], [https://www.ebi.ac.uk/pdbsum/1wge PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wge ProSAT], [https://www.topsan.org/Proteins/RSGI/1wge TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/DPH3_MOUSE DPH3_MOUSE] Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2. Down-regulation increases extracellular release of proteoglycans, indicating a possible role in the secretion process. Stimulates binding of GNEFR to SEC5 (By similarity). | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: Inoue | + | [[Category: Inoue M]] |
| - | [[Category: Kigawa | + | [[Category: Kigawa T]] |
| - | [[Category: Koshiba | + | [[Category: Koshiba S]] |
| - | [[Category: Nakanishi | + | [[Category: Nakanishi T]] |
| - | + | [[Category: Tochio N]] | |
| - | [[Category: Tochio | + | [[Category: Yokoyama S]] |
| - | [[Category: Yokoyama | + | |
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Current revision
Solution structure of the mouse DESR1
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Categories: Large Structures | Mus musculus | Inoue M | Kigawa T | Koshiba S | Nakanishi T | Tochio N | Yokoyama S
