This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1wxb
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
==Solution structure of the SH3 domain from human epidermal growth factor receptor pathway substrate 8-like protein== | ==Solution structure of the SH3 domain from human epidermal growth factor receptor pathway substrate 8-like protein== | ||
| - | <StructureSection load='1wxb' size='340' side='right'caption='[[1wxb | + | <StructureSection load='1wxb' size='340' side='right'caption='[[1wxb]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1wxb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1wxb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WXB FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wxb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxb OCA], [https://pdbe.org/1wxb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wxb RCSB], [https://www.ebi.ac.uk/pdbsum/1wxb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wxb ProSAT], [https://www.topsan.org/Proteins/RSGI/1wxb TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wxb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxb OCA], [https://pdbe.org/1wxb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wxb RCSB], [https://www.ebi.ac.uk/pdbsum/1wxb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wxb ProSAT], [https://www.topsan.org/Proteins/RSGI/1wxb TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/ES8L2_HUMAN ES8L2_HUMAN] Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.<ref>PMID:14565974</ref> | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 19: | Line 19: | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wxb ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wxb ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Epidermal growth factor receptor substrate 3D structures|Epidermal growth factor receptor substrate 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Chikayama | + | [[Category: Chikayama E]] |
| - | [[Category: Inoue | + | [[Category: Inoue M]] |
| - | [[Category: Kigawa | + | [[Category: Kigawa T]] |
| - | [[Category: Koshiba | + | [[Category: Koshiba S]] |
| - | [[Category: Muto | + | [[Category: Muto Y]] |
| - | + | [[Category: Yokoyama S]] | |
| - | [[Category: Yokoyama | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Solution structure of the SH3 domain from human epidermal growth factor receptor pathway substrate 8-like protein
| |||||||||||
Categories: Homo sapiens | Large Structures | Chikayama E | Inoue M | Kigawa T | Koshiba S | Muto Y | Yokoyama S
