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1x5y

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Current revision (14:01, 9 May 2024) (edit) (undo)
 
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==Solution structure of the fibronectin type-III domain of mouse myosin-binding protein C, Fast-type homolog==
==Solution structure of the fibronectin type-III domain of mouse myosin-binding protein C, Fast-type homolog==
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<StructureSection load='1x5y' size='340' side='right'caption='[[1x5y]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='1x5y' size='340' side='right'caption='[[1x5y]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1x5y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X5Y FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1x5y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X5Y FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mybpc2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x5y OCA], [https://pdbe.org/1x5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x5y RCSB], [https://www.ebi.ac.uk/pdbsum/1x5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x5y ProSAT], [https://www.topsan.org/Proteins/RSGI/1x5y TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x5y OCA], [https://pdbe.org/1x5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x5y RCSB], [https://www.ebi.ac.uk/pdbsum/1x5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x5y ProSAT], [https://www.topsan.org/Proteins/RSGI/1x5y TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MYPC2_MOUSE MYPC2_MOUSE]] Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role (By similarity).
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[https://www.uniprot.org/uniprot/MYPC2_MOUSE MYPC2_MOUSE] Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Inoue, M]]
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[[Category: Inoue M]]
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[[Category: Kigawa, T]]
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[[Category: Kigawa T]]
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[[Category: Koshiba, S]]
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[[Category: Koshiba S]]
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[[Category: Structural genomic]]
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[[Category: Tochio N]]
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[[Category: Tochio, N]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: Yoneyama M]]
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[[Category: Yoneyama, M]]
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[[Category: Cell adhesion]]
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[[Category: Cytoskeleton]]
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[[Category: Fast mybp-c]]
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[[Category: Fibronectin type iii domain containing protein]]
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[[Category: Muscle contraction]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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Current revision

Solution structure of the fibronectin type-III domain of mouse myosin-binding protein C, Fast-type homolog

PDB ID 1x5y

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