2ogd

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Current revision (10:38, 30 August 2023) (edit) (undo)
 
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<StructureSection load='2ogd' size='340' side='right'caption='[[2ogd]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='2ogd' size='340' side='right'caption='[[2ogd]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ogd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_(trypanozoon)_brucei Trypanosoma (trypanozoon) brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OGD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ogd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OGD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SUF:[2-(DIMETHYL-LAMBDA~4~-SULFANYL)-1-HYDROXYETHANE-1,1-DIYL]BIS(PHOSPHONIC+ACID)'>SUF</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ogc|2ogc]], [[2ogl|2ogl]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SUF:[2-(DIMETHYL-LAMBDA~4~-SULFANYL)-1-HYDROXYETHANE-1,1-DIYL]BIS(PHOSPHONIC+ACID)'>SUF</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/(2E,6E)-farnesyl_diphosphate_synthase (2E,6E)-farnesyl diphosphate synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.10 2.5.1.10] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ogd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogd OCA], [https://pdbe.org/2ogd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ogd RCSB], [https://www.ebi.ac.uk/pdbsum/2ogd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ogd ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ogd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogd OCA], [https://pdbe.org/2ogd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ogd RCSB], [https://www.ebi.ac.uk/pdbsum/2ogd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ogd ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q86C09_9TRYP Q86C09_9TRYP]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Cao, R]]
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[[Category: Trypanosoma brucei]]
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[[Category: Gao, Y]]
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[[Category: Cao R]]
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[[Category: Goddard, A]]
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[[Category: Gao Y]]
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[[Category: Oldfield, E]]
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[[Category: Goddard A]]
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[[Category: Robinson, H]]
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[[Category: Oldfield E]]
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[[Category: Protein-bisphosphonate complex]]
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[[Category: Robinson H]]
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[[Category: Transferase]]
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Current revision

T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-527

PDB ID 2ogd

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