3fe1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:28, 1 November 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='3fe1' size='340' side='right'caption='[[3fe1]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='3fe1' size='340' side='right'caption='[[3fe1]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3fe1]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FE1 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3fe1]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FE1 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HSPA6, HSP70B' ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fe1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fe1 OCA], [https://pdbe.org/3fe1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fe1 RCSB], [https://www.ebi.ac.uk/pdbsum/3fe1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fe1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fe1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fe1 OCA], [https://pdbe.org/3fe1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fe1 RCSB], [https://www.ebi.ac.uk/pdbsum/3fe1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fe1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/HSP76_HUMAN HSP76_HUMAN]] In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage (By similarity).
+
[https://www.uniprot.org/uniprot/HSP76_HUMAN HSP76_HUMAN] In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 26: Line 26:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Arrowsmith, C H]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Berg, S Van Den]]
+
[[Category: Berglund H]]
-
[[Category: Berglund, H]]
+
[[Category: Bountra C]]
-
[[Category: Bountra, C]]
+
[[Category: Collins R]]
-
[[Category: Collins, R]]
+
[[Category: Dahlgren LG]]
-
[[Category: Dahlgren, L G]]
+
[[Category: Edwards AM]]
-
[[Category: Edwards, A M]]
+
[[Category: Flodin S]]
-
[[Category: Flodin, S]]
+
[[Category: Flores A]]
-
[[Category: Flores, A]]
+
[[Category: Graslund S]]
-
[[Category: Graslund, S]]
+
[[Category: Hammarstrom M]]
-
[[Category: Hammarstrom, M]]
+
[[Category: Johansson A]]
-
[[Category: Johansson, A]]
+
[[Category: Johansson I]]
-
[[Category: Johansson, I]]
+
[[Category: Karlberg T]]
-
[[Category: Karlberg, T]]
+
[[Category: Kotenyova T]]
-
[[Category: Kotenyova, T]]
+
[[Category: Lehtio L]]
-
[[Category: Lehtio, L]]
+
[[Category: Moche M]]
-
[[Category: Moche, M]]
+
[[Category: Nilsson ME]]
-
[[Category: Nilsson, M E]]
+
[[Category: Nordlund P]]
-
[[Category: Nordlund, P]]
+
[[Category: Nyman T]]
-
[[Category: Nyman, T]]
+
[[Category: Persson C]]
-
[[Category: Persson, C]]
+
[[Category: Sagemark J]]
-
[[Category: Structural genomic]]
+
[[Category: Schueler H]]
-
[[Category: Sagemark, J]]
+
[[Category: Siponen MI]]
-
[[Category: Schueler, H]]
+
[[Category: Thorsell AG]]
-
[[Category: Siponen, M I]]
+
[[Category: Tresaugues L]]
-
[[Category: Thorsell, A G]]
+
[[Category: Van Den Berg S]]
-
[[Category: Tresaugues, L]]
+
[[Category: Weigelt J]]
-
[[Category: Weigelt, J]]
+
[[Category: Welin M]]
-
[[Category: Welin, M]]
+
[[Category: Wikstrom M]]
-
[[Category: Wikstrom, M]]
+
[[Category: Wisniewska M]]
-
[[Category: Wisniewska, M]]
+
-
[[Category: Atp-binding]]
+
-
[[Category: Chaperone]]
+
-
[[Category: Mixed beta-sheet]]
+
-
[[Category: Nucleotide-binding]]
+
-
[[Category: Polymorphism]]
+
-
[[Category: Sgc]]
+
-
[[Category: Stress response]]
+

Current revision

Crystal structure of the human 70kDa heat shock protein 6 (Hsp70B') ATPase domain in complex with ADP and inorganic phosphate

PDB ID 3fe1

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3fe1"
Personal tools