User:Elizabeth Sutherlin/Sandbox1

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(New page: ==Your Heading Here (maybe something like 'Structure')== <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> This is a default text for you...)
Current revision (20:41, 3 March 2022) (edit) (undo)
 
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==Your Heading Here (maybe something like 'Structure')==
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=''Homo Sapiens''=
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<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>
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<scene name='90/906205/Highlighting_residues_690-790/1'>Highlighting Residues 690-790</scene>
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This is the reference to the Ransey article. <ref name="Ransey"/>
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==Structure==
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<StructureSection load='7n00' size='350' frame='true'
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side='right' caption='Anaplastic Lymphoma Kinase' scene=’’>
This is a default text for your page '''Elizabeth Sutherlin/Sandbox1'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
This is a default text for your page '''Elizabeth Sutherlin/Sandbox1'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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== Function ==
== Function ==
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[https://www.nature.com/articles/s41586-021-04140-8 Mechanism of activation for ALK]
== Disease ==
== Disease ==
== Relevance ==
== Relevance ==
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===Background===
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[[Image:Full_ALK_bound_with_ALKAL2.png|400px|left|thumb|Figure1. The coolest image of this protein EVAH!!!|]]
== Structural highlights ==
== Structural highlights ==
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</StructureSection>
</StructureSection>
== References ==
== References ==
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<ref name="Ransey">PMID:28504306</ref>
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<ref>DOI: 10.1038/s41586-021-04140-8</ref>
<references/>
<references/>

Current revision

Homo Sapiens

This is the reference to the Ransey article. [1]

Structure

Anaplastic Lymphoma Kinase

Drag the structure with the mouse to rotate

References

[1] [4]

  1. 1.0 1.1 Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
  2. Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  3. Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
  4. Reshetnyak AV, Rossi P, Myasnikov AG, Sowaileh M, Mohanty J, Nourse A, Miller DJ, Lax I, Schlessinger J, Kalodimos CG. Mechanism for the activation of the anaplastic lymphoma kinase receptor. Nature. 2021 Dec;600(7887):153-157. doi: 10.1038/s41586-021-04140-8. Epub 2021, Nov 24. PMID:34819673 doi:http://dx.doi.org/10.1038/s41586-021-04140-8

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Elizabeth Sutherlin

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